PEN-G ACYLASE CATALYZED RESOLUTION OF PHENYLACETATE ESTERS OF SECONDARY ALCOHOLS

被引：44

作者：

BALDARO, E

DARRIGO, P

PEDROCCHIFANTONI, G

ROSELL, CM

SERVI, S

TAGLIANI, A

TERRENI, M

机构：

[1] DIPARTIMENTO CHIM, CNR, CTR STUDIO SOSTANZE ORGAN NAT, VIA MANCINELLI 7, I-20131 MILAN, ITALY

[2] RECORDATI SPA, UNITA BI, I-20060 CASSINA DE PECCHI, ITALY

[3] CSIC, IST CATALISIS & PETROLQUIM, MADRID 6, SPAIN

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 05期

关键词：

PENICILLIN ACYLASE; KINETIC RESOLUTION; HYDROLYSIS;

D O I：

10.1016/S0957-4166(00)80148-2

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Penicillin G acylase from E. coli (E.C. 3.5.1.11.) immobilized on Eupergit C is used for the kinetic resolution of phenyl acetate esters of secondary alcohols of pharmaceutical interest.

引用

页码：1031 / 1034

页数：4

共 16 条

[1]

BALDARO E, 1992, NATO ADV SCI I C-MAT, V381, P175

[2] PHENYLACETYLOXYMETHYLENE, A CARBOXYL PROTECTING GROUP REMOVABLE WITH IMMOBILIZED PENICILLIN ACYLASE, USEFUL IN BENZYL PENICILLIN CHEMISTRY [J].

BALDARO, E ;

FAIARDI, D ;

FUGANTI, C ;

GRASSELLI, P ;

LAZZARINI, A .

TETRAHEDRON LETTERS, 1988, 29 (36) :4623-4624

[3]

BOAZ NW, 1992, J ORG CHEM, V57, P4286

[4]

DITZIAPETRIS R, 1991, FEBS LETT, V287, P31

[5] IMMOBILIZED BENZYLPENICILLIN ACYLASE - APPLICATION TO THE SYNTHESIS OF OPTICALLY-ACTIVE FORMS OF CARNITIN AND PROPRANALOL [J].

FUGANTI, C ;

GRASSELLI, P ;

SENECI, PF ;

SERVI, S ;

CASATI, P .

TETRAHEDRON LETTERS, 1986, 27 (18) :2061-2062

[6] ENANTIOSELECTIVE RECOGNITION OF THE PHENACETYL MOIETY IN THE PEN-G ACYLASE CATALYZED-HYDROLYSIS OF PHENYLACETATE ESTERS [J].

FUGANTI, C ;

ROSELL, CM ;

SERVI, S ;

TAGLIANI, A ;

TERRENI, M .

TETRAHEDRON-ASYMMETRY, 1992, 3 (03) :383-386

[7] IMMOBILIZED PENICILLINACYLASE - APPLICATION TO THE SYNTHESIS OF THE DIPEPTIDE ASPARTAME [J].

FUGANTI, C ;

GRASSELLI, P ;

CASATI, P .

TETRAHEDRON LETTERS, 1986, 27 (27) :3191-3194

[8] PENICILLINACYLASE AND ALPHA-CHYMOTRYPSIN CATALYZED-HYDROLYSIS OF PHENYLACETATE AND PHENYLPROPIONATE ESTERS OF 2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOLS [J].

FUGANTI, C ;

GRASSELLI, P ;

SERVI, S ;

LAZZARINI, A ;

CASATI, P .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (08) :538-539

[9] SUBSTRATE-SPECIFICITY AND ENANTIOSELECTIVITY OF PENICILLINACYLASE CATALYZED-HYDROLYSIS OF PHENACETYL ESTERS OF SYNTHETICALLY USEFUL CARBINOLS [J].

FUGANTI, C ;

GRASSELLI, P ;

SERVI, S ;

LAZZARINI, A ;

CASATI, P .

TETRAHEDRON, 1988, 44 (09) :2575-2582

[10] APPROACH TO THE USE OF BENZYLPENICILLINACYLASE FOR CONFIGURATIONAL CORRELATIONS OF AMINO-COMPOUNDS .2. HYDROLYSIS OF N-(PARA-AMINOPHENYLACETYL) DERIVATIVES OF SOME CHIRAL PRIMARY AMINES [J].

ROSSI, D ;

CALCAGNI, A ;

ROMEO, A .

JOURNAL OF ORGANIC CHEMISTRY, 1979, 44 (13) :2222-2225

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