Current Developments in Cellulase Engineering

被引：7

作者：

Kellermann, Stefanie Julia ^{[1
]}

Rentmeister, Andrea ^{[1
]}

机构：

[1] Univ Munster, Inst Biochem, Dept Chem, D-48149 Munster, Germany

来源：

CHEMBIOENG REVIEWS | 2014年 / 1卷 / 01期

关键词：

Biofuel; Cellulase; Cellulose degradation; Cellulosome; Consolidated bioprocessing;

D O I：

10.1002/cben.201300006

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Degradation of cellulose represents a key step for efficient generation of biofuels such as ethanol or butanol from nonfood crops. Several strategies aim to improve the performance of cellulases in order to make the overall process more cost-efficient. In one strategy, novel arrangements of cellulases are developed. The resulting so-called designer cellulosomes might allow to equip the fermenting hosts with sufficient cellulase activity to grow on cellulose as sole carbon source and thus enable consolidated bioprocessing. Other strategies aim to engineer cellulases with higher thermostability and activity to make cellulose hydrolysis more efficient. This review summarizes current developments in the field of cellulase engineering and highlight achievements as well as limitations.

引用

页码：6 / 13

页数：8

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