CHANGING CHEMOSUSCEPTIBILITY IN THE 2ND-STAGE LARVAE OF TOXOCARA-CANIS BY LONG-TERM INCUBATION

被引：2

作者：

AKAO, N ^{[1
]}

GOTO, Y ^{[1
]}

KONDO, K ^{[1
]}

TSUDA, Y ^{[1
]}

机构：

[1] KANAZAWA UNIV,FAC PHARMACEUT SCI,KANAZAWA,ISHIKAWA 920,JAPAN

来源：

JOURNAL OF HELMINTHOLOGY | 1993年 / 67卷 / 02期

关键词：

TOXOCARA-CANIS; CITRAL; DECANOIC ACID; TANNIC ACID; CHEMOSUSCEPTIBILITY; NEMATODA; 2ND-STAGE LARVAE;

D O I：

10.1017/S0022149X00013031

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Second-stage larvae of Toxocara canis were maintained in vitro for one year. Susceptibility of the larvae to drugs was evaluated by means of minimal larvicidal concentration (MLC) and larval bursting percentage. MLCs of citral and decanoic acid were almost constant throughout all stages of incubation. However, bursting percentage markedly varied within the first 20 weeks of incubation. Therefore, while larvae are available for use in the MLC assay at any stage of incubation, those beyond the first 20 weeks after incubation should be used for the bursting assay to obtain reproducible results.

引用

页码：145 / 150

页数：6

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