Construction, quality assurance and calibration of spherical isotropic fibre optic light diffusers

被引：42

作者：

VanStaveren, HJ

Marijnissen, HPA

Aalders, MCG

Star, WM

机构：

[1] PDT Research Laboratory, Department of Clinical Physics, Daniel den Hoed Cancer Centre, AE Rotterdam, 3008

来源：

LASERS IN MEDICAL SCIENCE | 1995年 / 10卷 / 02期

关键词：

photodynamic therapy; isotropic fibre optic light diffusers; construction of diffusers; quality assurance of diffusers; Calibration of diffusers; goniometer; integrating sphere;

D O I：

10.1007/BF02150852

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Spherical isotropic fibre optic light diffusers are used in photodynamic therapy either as a light source or as a light detector. The construction of light diffusers using different materials is described, viz. an optical method involving local polymerization of a dental fissure sealant, which is referred to as the Henderson method, and a second method using plastic or ceramic prefabricated spheres. Quality tests necessary for reliable clinical use are presented for the mechanical strength, output power and isotropy. The maximum pull-off force and blow-off output power for the different kinds of diffusers were determined. The calibration procedures are given for measurement of the output power and wavelength of the light emitted by a diffuser and for measurement of the fluence rate by a light-detecting diffuser, using a compact integrating sphere device. With all types of diffusers described, an isotropy can be obtained of better than +/-20% measured over a 320 degrees angle for spheres as small as approximate to 1 mm. Larger ceramic diffusers are particularly suitable for delivering high output powers. A 3-mm-diameter ceramic diffuser mounted on a 600-mu m-core fibre can emit up to approximate to 5 W of continuous wave (CW) visible light in air. Diffusers used for light detection can measure the light fluence rate in tissue with approximate to 15% accuracy or better if calibration factors are determined for each individual probe.

引用

页码：137 / 147

页数：11

共 17 条

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