Image-Based Treatment Planning of the Post-Lumpectomy Breast Utilizing CT and 3TMRI

被引:15
作者
Jacobson, Geraldine [1 ]
Zamba, Gideon [2 ]
Betts, Vicki [1 ]
Muruganandham, M. [1 ]
Buechler-Price, Joni [1 ]
机构
[1] Univ Iowa Hosp & Clin, Dept Radiat Oncol, 200 Hawkins Dr, Iowa City, IA 52242 USA
[2] Univ Iowa, Dept Biostat, Coll Publ Hlth, Iowa City, IA 52242 USA
关键词
D O I
10.4061/2011/246265
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Accurate lumpectomy cavity definition is critical in breast treatment planning. We compared contouring lumpectomy cavity volume and cavity visualization score (CVS) with CT versus 3T MRI. 29 patients were imaged with CT and 3T MRI. Seven additional boost planning sets were obtained for 36 image sets total. Three observers contoured the lumpectomy cavity on all images, assigning a cavity visualization score (CVS) of 1 to 5. Measures of consistency and agreement for CT volumes were 98.84% and 98.62%, for T1 MRI were 95.65% and 95.55%, and for T2 MRI were 97.63% and 97.71%. The mean CT, T1 MRI, and T2 MRI CVS scores were 3.28, 3.38, and 4.32, respectively. There was a highly significant difference between CT and T2 scores (P < .00001) and between T1 and T2 scores (P < .00001). Interobserver consistency and agreement regarding volumes were high for all three modalities with T2 MRI CVS the highest. MRI may contribute to target definition in selected patients.
引用
收藏
页数:5
相关论文
共 15 条
[1]   MRI GUIDANCE FOR ACCELERATED PARTIAL BREAST IRRADIATION IN PRONE POSITION: IMAGING PROTOCOL DESIGN AND EVALUATION [J].
Ahn, Kang-Hyun ;
Hargreaves, Brian A. ;
Alley, Marcus T. ;
Horst, Kathleen C. ;
Luxton, Gary ;
Daniel, Bruce L. ;
Hristov, Dimitre .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 75 (01) :285-293
[2]   Evaluating the impact of preoperative breast magnetic resonance imaging on the surgical management of newly diagnosed breast cancers - Discussion [J].
Grube, Baiba J. ;
Bethke, Kevin P. ;
Harken, Alden H. ;
Velasco, Jose M. .
ARCHIVES OF SURGERY, 2007, 142 (05) :445-447
[3]   Magnetic resonance imaging of the breast prior to biopsy [J].
Bluemke, DA ;
Gatsonis, CA ;
Chen, MH ;
DeAngelis, GA ;
DeBruhl, N ;
Harms, S ;
Heywang-Köbrunner, SH ;
Hylton, N ;
Kuhl, CK ;
Lehman, C ;
Pisano, ED ;
Causer, P ;
Schnitt, SJ ;
Smazal, SF ;
Stelling, CB ;
Weatherall, PT ;
Schnall, MD .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (22) :2735-2742
[4]   Definition of postlumpectomy tumor bed for radiotherapy boost field planning: CT versus surgical clips [J].
Goldberg, H ;
Prosnitz, RG ;
Olson, JA ;
Marks, LB .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2005, 63 (01) :209-213
[5]   TUMOR BED DELINEATION FOR PARTIAL BREAST AND BREAST BOOST RADIOTHERAPY PLANNED IN THE PRONE POSITION: WHAT DOES MRI ADD TO X-RAY CT LOCALIZATION OF TITANIUM CLIPS PLACED IN THE EXCISION CAVITY WALL? [J].
Kirby, Anna M. ;
Yarnold, John R. ;
Evans, Philip M. ;
Morgan, Veronica A. ;
Schmidt, Maria A. ;
Scurr, Erica D. ;
deSouza, Nandita M. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 74 (04) :1276-1282
[6]   Variability among breast radiation oncologists in delineation of the postsurgical lumpectomy cavity [J].
Landis, Daniel M. ;
Luo, Weixiu ;
Song, Jun ;
Bellon, Jennifer R. ;
Punglia, Rinaa S. ;
Wong, Julia S. ;
Killoran, Joseph H. ;
Gelman, Rebecca ;
Harris, Jay R. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 67 (05) :1299-1308
[7]   VARIABILITY OF TARGET AND NORMAL STRUCTURE DELINEATION FOR BREAST CANCER RADIOTHERAPY: AN RTOG MULTI-INSTITUTIONAL AND MULTIOBSERVER STUDY [J].
Li, X. Allen ;
Tai, An ;
Arthur, Douglas W. ;
Buchholz, Thomas A. ;
Macdonald, Shannon ;
Marks, Lawrence B. ;
Moran, Jean M. ;
Pierce, Lori J. ;
Rabinovitch, Rachel ;
Taghian, Alphonse ;
Vicini, Frank ;
Woodward, Wendy ;
White, Julia R. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 73 (03) :944-951
[8]   MR imaging findings in the contralateral breast of women with recently diagnosed breast cancer [J].
Liberman, L ;
Morris, EA ;
Kim, CM ;
Kaplan, JB ;
Abramson, AF ;
Menell, JH ;
Van Zee, KJ ;
Dershaw, DD .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2003, 180 (02) :333-341
[9]   Clinical variability of target volume description in conformal radiotherapy planning [J].
Logue, JP ;
Sharrock, CL ;
Cowan, RA ;
Read, G ;
Marrs, J ;
Mott, D .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1998, 41 (04) :929-932
[10]   Target volume delineation for partial breast radiotherapy planning: Clinical characteristics associated with low interobserver concordance [J].
Petersen, Ross P. ;
Truong, Pauline T. ;
Kader, Hosam A. ;
Berthelet, Eric ;
Lee, Junella C. ;
Hilts, Michelle L. ;
Kader, Adam S. ;
Beckham, Wayne A. ;
Olivotto, Ivo A. .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2007, 69 (01) :41-48