COUPLING OF BETA-CELL DESENSITIZATION BY HYPERGLYCEMIA TO EXCESSIVE STIMULATION AND CIRCULATING INSULIN IN GLUCOSE-INFUSED RATS

被引：107

作者：

SAKO, Y ^{[1
]}

GRILL, VE ^{[1
]}

机构：

[1] KAROLINSKA HOSP,DEPT ENDOCRINOL,S-10401 STOCKHOLM 60,SWEDEN

来源：

DIABETES | 1990年 / 39卷 / 12期

关键词：

D O I：

10.2337/diabetes.39.12.1580

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1580 / 1583

页数：4

共 14 条

[1]

AMMON HPT, 1976, ENDOCRINOLOGY, V99, P1469

[2] THE 3RD PHASE OF INVITRO INSULIN-SECRETION - EVIDENCE FOR GLUCOSE INSENSITIVITY [J].

BOLAFFI, JL ;

HELDT, A ;

LEWIS, LD ;

GRODSKY, GM .

DIABETES, 1986, 35 (03) :370-373

[3] FEEDBACK INHIBITION OF INSULIN ON INSULIN-SECRETION IN ISOLATED PANCREATIC-ISLETS [J].

DRAZNIN, B ;

GOODMAN, M ;

LEITNER, JW ;

SUSSMAN, KE .

ENDOCRINOLOGY, 1986, 118 (03) :1054-1058

[4] B-CELL INSENSITIVITY IN A RAT MODEL OF NON-INSULIN-DEPENDENT DIABETES - EVIDENCE FOR A RAPIDLY REVERSIBLE EFFECT OF PREVIOUS HYPERGLYCEMIA [J].

GRILL, V ;

WESTBERG, M ;

OSTENSON, CG .

JOURNAL OF CLINICAL INVESTIGATION, 1987, 80 (03) :664-669

[5] LOSS OF A PRIMING EFFECT OF GLUCOSE ON A-CELL AND D-CELL SECRETION IN PERFUSED PANCREASES FROM ALLOXAN-DIABETIC RATS - ROLE OF INSULIN AND ALLOXAN [J].

GRILL, V ;

EFENDIC, S .

DIABETOLOGIA, 1983, 24 (01) :47-51

[6] COATED CHARCOAL IMMUNOASSAY OF INSULIN [J].

HERBERT, V ;

LAU, KS ;

GOTTLIEB, CW ;

BLEICHER, SJ .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1965, 25 (10) :1375-+

[7] ISLET B-CELL DYSFUNCTION AND THE TIME COURSE OF RECOVERY FOLLOWING CHRONIC OVERINSULINIZATION OF NORMAL RATS [J].

KRUSZYNSKA, YT ;

VILLAKOMAROFF, L ;

HALBAN, PA .

DIABETOLOGIA, 1988, 31 (08) :621-626

[8] CHRONIC HYPERGLYCEMIA IS ASSOCIATED WITH IMPAIRED GLUCOSE INFLUENCE ON INSULIN-SECRETION - A STUDY IN NORMAL RATS USING CHRONIC INVIVO GLUCOSE INFUSIONS [J].

LEAHY, JL ;

COOPER, HE ;

DEAL, DA ;

WEIR, GC .

JOURNAL OF CLINICAL INVESTIGATION, 1986, 77 (03) :908-915

[9] EXPERIMENTAL STUDY ON GLIBENCLAMIDE (HB 419) A NEW PARTICULARLY ACTIVE HYPOGLYCAEMIC SULPHONAMIDE .I. BETA-CYTROTROPIC ACTION AND INSULIN SECRETION [J].

LOUBATIE.A ;

MARIANI, MM ;

RIBES, G ;

DEMALBOS.H ;

CHAPAL, J .

DIABETOLOGIA, 1969, 5 (01) :1-&

[10]

ROOS KA, 1981, ACTA CHIR SCAND, V147, P459

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