UNUSUAL CUTANEOUS MANIFESTATIONS OF MYELODYSPLASTIC SYNDROME

被引：49

作者：

SUZUKI, Y ^{[1
]}

KURODA, K ^{[1
]}

KOJIMA, T ^{[1
]}

FUJITA, M ^{[1
]}

ISEKI, T ^{[1
]}

SHINKAI, H ^{[1
]}

机构：

[1] CHIBA UNIV,SCH MED,DEPT INTERNAL MED 1,CHUO KU,CHIBA 260,JAPAN

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1995年 / 133卷 / 03期

关键词：

D O I：

10.1111/j.1365-2133.1995.tb02684.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report a 58-year-old patient with acute myeloid leukaemia who developed an oedematous erythema resembling Sweet's syndrome, accompanied by atypical erythema nodosum and bullous pyoderma gangrenosum. Examination of skin biopsies showed dense infiltration with mature neutrophils, although there was peripheral blood leucocytopenia. The oedematous erythema worsened after he was treated with granulocyte-colony-stimulating factor (G-CSF), which was given for his leucocytopenia. We suggest that when a neutrophilic dermatosis complicates leukaemia, alternatives to G-CSF should be considered for the treatment of leucocytopenia. Corticosteroids were very effective in controlling the skin lesions in our patient.

引用

页码：483 / 486

页数：4

共 17 条

[1]

BURTON JL, 1976, BRIT J DERMATOL, V95, P209

[2] NEUTROPHILIC DERMATOSIS OF MYELOPROLIFERATIVE DISORDERS - ATYPICAL FORMS OF PYODERMA GANGRENOSUM AND SWEETS SYNDROME ASSOCIATED WITH MYELOPROLIFERATIVE DISORDERS [J].

CAUGHMAN, W ;

STERN, R ;

HAYNES, H .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1983, 9 (05) :751-758

[3]

COHEN PR, 1992, J RHEUMATOL, V19, P814

[4] GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR AND VASCULITIS [J].

DREICER, R ;

SCHILLER, JH ;

CARBONE, PP .

ANNALS OF INTERNAL MEDICINE, 1989, 111 (01) :91-92

[5] NEUTROPHILIC DERMATOSES AND MYELOPROLIFERATIVE DISEASE - REPORT OF 2 CASES [J].

GIBSON, LE ;

DICKEN, CH ;

FLACH, DB .

MAYO CLINIC PROCEEDINGS, 1985, 60 (11) :735-740

[6] THERAPY FOR NEUTROPENIA IN HAIRY-CELL LEUKEMIA WITH RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR [J].

GLASPY, JA ;

BALDWIN, GC ;

ROBERTSON, PA ;

SOUZA, L ;

VINCENT, M ;

AMBERSLEY, J ;

GOLDE, DW .

ANNALS OF INTERNAL MEDICINE, 1988, 109 (10) :789-795

[7] LEUKOCYTE COLONY-STIMULATING FACTORS - A REVIEW OF ASSOCIATED NEUTROPHILIC DERMATOSES AND VASCULITIDES [J].

JOHNSON, MML ;

GRIMWOOD, RE .

ARCHIVES OF DERMATOLOGY, 1994, 130 (01) :77-81

[8]

MALE D, 1991, ADV IMMUNOL, P11

[9] NEUTROPHILIC DERMATOSIS WITH MYELODYSPLASTIC SYNDROME - NUCLEAR SEGMENTATION ANOMALIES OF NEUTROPHILS IN THE SKIN LESION AND IN PERIPHERAL-BLOOD [J].

MORIOKA, N ;

OTSUKA, F ;

NOGITA, T ;

IGISU, K ;

URABE, A ;

ISHIBASHI, Y .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1990, 23 (02) :247-249

[10] THE SWEET SYNDROME DURING THERAPY WITH GRANULOCYTE COLONY-STIMULATING FACTOR [J].

PARK, JW ;

MEHROTRA, B ;

BARNETT, BO ;

BARON, AD ;

VENOOK, AP .

ANNALS OF INTERNAL MEDICINE, 1992, 116 (12) :996-998

← 1 2 →