PROGNOSTIC VALUE OF SERUM THYMIDINE KINASE, TISSUE POLYPEPTIDE ANTIGEN AND NEURON SPECIFIC ENOLASE IN PATIENTS WITH SMALL-CELL LUNG-CANCER

被引：29
作者：
VANDERGAAST, A
VANPUTTEN, WLJ
OOSTEROM, R
COZIJNSEN, M
HOEKSTRA, R
SPLINTER, TAW
机构：
[1] DR DANIEL DEN HOED CANC CTR,DEPT BIOSTAT,ROTTERDAM,NETHERLANDS
[2] DR DANIEL DEN HOED CANC CTR,DEPT CLIN CHEM,ROTTERDAM,NETHERLANDS
来源：
BRITISH JOURNAL OF CANCER | 1991年 / 64卷 / 02期
关键词：
D O I：
10.1038/bjc.1991.309
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In a group of seventy patients with small cell lung cancer the prognostic value of serum tumour markers was determined. Thymidine kinase (TK), tissue polypeptide antigen (TPA) and lactate dehydrogenase (LDH) but not neuron specific enolase (NSE) correlated significantly with survival. Since all markers were strongly interrelated with each other and with the extent of disease, the combined determination of TK, TPA and LDH or the combination of disease extent and a marker yielded no more prognostic information than a single measurement of one of these variables.
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页码：369 / 372
页数：4
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