THE ANTIVIRAL EFFECT OF ZIDOVUDINE AND RIBAVIRIN IN CLINICAL-TRIALS AND THE USE OF P24 ANTIGEN LEVELS AS A VIROLOGIC MARKER

被引：78

作者：

SPECTOR, SA

KENNEDY, C

MCCUTCHAN, JA

BOZZETTE, SA

STRAUBE, RG

CONNOR, JD

RICHMAN, DD

机构：

[1] UNIV CALIF SAN DIEGO, SCH MED, MED CTR, DEPT MED, SAN DIEGO, CA 92103 USA

[2] UNIV CALIF SAN DIEGO, SCH MED, MED CTR, DEPT PATHOL, SAN DIEGO, CA 92103 USA

来源：

JOURNAL OF INFECTIOUS DISEASES | 1989年 / 159卷 / 05期

关键词：

D O I：

10.1093/infdis/159.5.822

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：822 / 828

页数：7

共 19 条

[1] RIBAVIRIN TREATMENT OF THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME (AIDS) AND THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME-RELATED COMPLEX (ARC) - A PHASE-1 STUDY SHOWS TRANSIENT CLINICAL IMPROVEMENT ASSOCIATED WITH SUPPRESSION OF THE HUMAN-IMMUNODEFICIENCY-VIRUS AND ENHANCED LYMPHOCYTE-PROLIFERATION [J].

CRUMPACKER, C ;

HEAGY, W ;

BUBLEY, G ;

MONROE, JE ;

FINBERG, R ;

HUSSEY, S ;

SCHNIPPER, L ;

LUCEY, D ;

LEE, TH ;

MCLANE, MF ;

ESSEX, M ;

MULDER, C .

ANNALS OF INTERNAL MEDICINE, 1987, 107 (05) :664-674

[2] RISK OF AIDS RELATED COMPLEX AND AIDS IN HOMOSEXUAL MEN WITH PERSISTENT HIV ANTIGENEMIA [J].

DEWOLF, F ;

GOUDSMIT, J ;

PAUL, DA ;

LANGE, JMA ;

HOOIJKAAS, C ;

SCHELLEKENS, P ;

COUTINHO, RA ;

VANDERNOORDAA, J .

BMJ-BRITISH MEDICAL JOURNAL, 1987, 295 (6598) :569-572

[3] NATURAL-HISTORY OF HUMAN IMMUNODEFICIENCY VIRUS-INFECTIONS IN HEMOPHILIACS - EFFECTS OF T-CELL SUBSETS, PLATELET COUNTS, AND AGE [J].

EYSTER, ME ;

GAIL, MH ;

BALLARD, JO ;

ALMONDHIRY, H ;

GOEDERT, JJ .

ANNALS OF INTERNAL MEDICINE, 1987, 107 (01) :1-6

[4] CURRENT ISSUES IN DEVELOPING A STRATEGY FOR DEALING WITH THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME [J].

FAUCI, AS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (24) :9278-9283

[5] THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

FISCHL, MA ;

RICHMAN, DD ;

GRIECO, MH ;

GOTTLIEB, MS ;

VOLBERDING, PA ;

LASKIN, OL ;

LEEDOM, JM ;

GROOPMAN, JE ;

MILDVAN, D ;

SCHOOLEY, RT ;

JACKSON, GG ;

DURACK, DT ;

KING, D .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) :185-191

[6]

GOUDSMIT J, 1986, LANCET, V2, P177

[7] CHARACTERIZATION OF THE AIDS-ASSOCIATED RETROVIRUS REVERSE-TRANSCRIPTASE AND OPTIMAL CONDITIONS FOR ITS DETECTION IN VIRIONS [J].

HOFFMAN, AD ;

BANAPOUR, B ;

LEVY, JA .

VIROLOGY, 1985, 147 (02) :326-335

[8] HUMAN IMMUNODEFICIENCY VIRUS (HIV) ANTIGENEMIA (P24) IN THE ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) AND THE EFFECT OF TREATMENT WITH ZIDOVUDINE (AZT) [J].

JACKSON, GG ;

PAUL, DA ;

FALK, LA ;

RUBENIS, M ;

DESPOTES, JC ;

MACK, D ;

KNIGGE, M ;

EMESON, EE .

ANNALS OF INTERNAL MEDICINE, 1988, 108 (02) :175-180

[9] INFECTION WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS - CLINICAL MANIFESTATIONS AND THEIR RELATIONSHIP TO IMMUNE-DEFICIENCY - A REPORT FROM THE MULTICENTER AIDS COHORT STUDY [J].

KASLOW, RA ;

PHAIR, JP ;

FRIEDMAN, HB ;

LYTER, D ;

SOLOMON, RE ;

DUDLEY, J ;

POLK, BF ;

BLACKWELDER, W .

ANNALS OF INTERNAL MEDICINE, 1987, 107 (04) :474-480

[10] PERSISTENT HIV ANTIGENEMIA AND DECLINE OF HIV CORE ANTIBODIES ASSOCIATED WITH TRANSITION TO AIDS [J].

LANGE, JMA ;

PAUL, DA ;

HUISMAN, HG ;

DEWOLF, F ;

VANDENBERG, H ;

COUTINHO, RA ;

DANNER, SA ;

VANDERNOORDAA, J ;

GOUDSMIT, J .

BRITISH MEDICAL JOURNAL, 1986, 293 (6560) :1459-1462

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