Radiation sterilization of new drug delivery systems

被引：31
作者：
Abuhanoglu, Gusrhan [1 ]
Ozer, A. Yekta [1 ]
机构：
[1] Hacettepe Univ, Fac Pharm, Dept Radiopharm, TR-06100 Ankara, Turkey
来源：
INTERVENTIONAL MEDICINE AND APPLIED SCIENCE | 2014年 / 6卷 / 02期
关键词：
radiation sterilization; e-beam sterilization; sterilization by gamma radiation; neutron radiation (e-beam) sterilization; new drug delivery systems;
D O I：
10.1556/IMAS.6.2014.2.1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Radiation sterilization has now become a commonly used method for sterilization of several active ingredients in drugs or drug delivery systems containing these substances. In this context, many applications have been performed on the human products that are required to be sterile, as well as on pharmaceutical products prepared to be developed. The new drug delivery systems designed to deliver the medication to the target tissue or organ, such as microspheres, nanospheres, microemulsion, and liposomal systems, have been sterilized by gamma (gamma) and beta (beta) rays, and more recently, by e-beam sterilization. In this review, the sterilization of new drug delivery systems was discussed other than conventional drug delivery systems by. irradiation.
引用
收藏
页码：51 / 60
页数：10
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