SPECIFIC AMINO-ACID SUBSTITUTIONS IN BACTERIOOPSIN - REPLACEMENT OF A RESTRICTION FRAGMENT IN THE STRUCTURAL GENE BY SYNTHETIC DNA FRAGMENTS CONTAINING ALTERED CODONS

被引:162
作者
LO, KM [1 ]
JONES, SS [1 ]
HACKETT, NR [1 ]
KHORANA, HG [1 ]
机构
[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139
来源
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1984年 / 81卷 / 08期
关键词
D O I
10.1073/pnas.81.8.2285
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:2285 / 2289
页数:5
相关论文
共 32 条
[1]   SITE OF ATTACHMENT OF RETINAL IN BACTERIORHODOPSIN [J].
BAYLEY, H ;
HUANG, KS ;
RADHAKRISHNAN, R ;
ROSS, AH ;
TAKAGAKI, Y ;
KHORANA, HG .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (04) :2225-2229
[2]   DEOXYNUCLEOSIDE PHOSPHORAMIDITES - A NEW CLASS OF KEY INTERMEDIATES FOR DEOXYPOLYNUCLEOTIDE SYNTHESIS [J].
BEAUCAGE, SL ;
CARUTHERS, MH .
TETRAHEDRON LETTERS, 1981, 22 (20) :1859-1862
[3]  
BIRNBOIM HC, 1979, NUCLEIC ACIDS RES, V7, P1513
[4]  
Brown E L, 1979, Methods Enzymol, V68, P109
[5]  
CARUTHERS MH, 1982, CHEM ENZYMATIC SYNTH, P71
[6]   OLIGONUCLEOTIDE-DIRECTED MUTAGENESIS AS A GENERAL AND POWERFUL METHOD FOR STUDIES OF PROTEIN FUNCTION [J].
DALBADIEMCFARLAND, G ;
COHEN, LW ;
RIGGS, AD ;
MORIN, C ;
ITAKURA, K ;
RICHARDS, JH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (21) :6409-6413
[7]   A PROTON MOTIVE FORCE TRANSDUCER AND ITS ROLE IN PROTON PUMPS, PROTON ENGINES, TOBACCO MOSAIC-VIRUS ASSEMBLY AND HEMOGLOBIN ALLOSTERISM [J].
DUNKER, AK .
JOURNAL OF THEORETICAL BIOLOGY, 1982, 97 (01) :95-127
[8]   THE BACTERIORHODOPSIN GENE [J].
DUNN, R ;
MCCOY, J ;
SIMSEK, M ;
MAJUMDAR, A ;
CHANG, SH ;
RAJBHANDARY, UL ;
KHORANA, HG .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (11) :6744-6748
[9]  
DUNN RJ, 1984, COLD SPRING HARBOR S, V48
[10]   BACTERIORHODOPSIN IS AN INSIDE-OUT PROTEIN [J].
ENGELMAN, DM ;
ZACCAI, G .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (10) :5894-5898