EOSINOPHIL CATIONIC PROTEIN IN THE SERA OF PATIENTS WITH MYCOPLASMA-PNEUMONIA

被引：10

作者：

YAMASHITA, R ^{[1
]}

KITAHARA, H ^{[1
]}

KANEMITSU, T ^{[1
]}

TAKEDA, T ^{[1
]}

YAMAGUCHI, S ^{[1
]}

机构：

[1] KEIO UNIV,SCH MED,TOKYO,JAPAN

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 1994年 / 13卷 / 05期

关键词：

EOSINOPHIL CATIONIC PROTEIN; MYCOPLASMA PNEUMONIA; ASTHMA; EOSINOPHILIA;

D O I：

10.1097/00006454-199405000-00009

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In 1985 we reported that eosinophilia was found in many children with Mycoplasma pneumonia, We measured the serum concentrations of eosinophil cationic protein (ECP) produced by eosinophils in 25 children with Mycoplasma pneumonia, 25 with asthma and 11 with no disease (normal controls). The mean concentrations (+/-SD) of serum ECP in children with Mycoplasma pneumonia, with asthma and the normal controls were 18.7 +/- 12.6, 23.7 +/- 12.2 and 6.5 +/- 1.4 mu g/ml, respectively. When compared with those of normal controls, these higher serum concentrations of ECP in children with Mycoplasma pneumonia and asthma were statistically significant (P < 0.001). The data were directly correlated with the presence of eosinophilia (r = 0.349). There was no relationship between the amount of ECP and the age of children with Mycoplasma pneumonia. These results suggest that ECP may work as a factor causing a persistent cough similar to asthma in children with Mycoplasma pneumonia.

引用

页码：379 / 381

页数：3

共 15 条

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