SYNTHESIS OF FLUORINE-CONTAINING ISOSTERES OF SPHINGOSINE AS INACTIVATORS OF PROTEIN KINASE-C

被引:29
作者
KOZIKOWSKI, AP [1 ]
WU, JP [1 ]
机构
[1] UNIV PITTSBURGH,CHEVRON SCI CTR,DEPT BEHAV NEUROSCI,PITTSBURGH,PA 15260
关键词
D O I
10.1016/S0040-4039(00)97608-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Syntheses of isosteres of D-sphingosine in which either the primary or the secondary hydroxyl group of the parent compound has been replaced by a fluorine substituent are described. © 1990.
引用
收藏
页码:4309 / 4312
页数:4
相关论文
共 50 条
[21]   SYNTHESIS OF FLUORINE-CONTAINING HETEROCYCLIC NITRAMINES [J].
YOUNG, JA ;
SCHMIDTC.JJ ;
KRIMMEL, JA .
JOURNAL OF ORGANIC CHEMISTRY, 1971, 36 (02) :347-&
[22]   SYNTHESIS OF FLUORINE-CONTAINING POLY(ARYLETHERS) [J].
IRVIN, JA ;
LEE, AR ;
FITCH, JW ;
CASSIDY, PE .
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1993, 206 :281-PMSE
[23]   Synthesis of fluorine-containing prenylated benzophenones [J].
Mzozoyana, Vuyisa ;
van Heerden, Fanie R. .
SYNTHETIC COMMUNICATIONS, 2020, 50 (14) :2226-2235
[24]   SYNTHESIS AND PROPERTIES OF FLUORINE-CONTAINING POLYAMIDES [J].
MALICHENKO, BF ;
TSYPINA, ON ;
CHERVYAT.LL ;
KACHAN, AA .
VYSOKOMOLEKULYARNYE SOEDINENIYA SERIYA A, 1974, 16 (08) :1787-1791
[25]   SYNTHESIS OF NOVEL FLUORINE-CONTAINING CEPHALOSPORINS [J].
NISHIDE, K ;
KOBORI, T ;
TUNEMOTO, D ;
KONDO, K .
HETEROCYCLES, 1987, 26 (03) :633-640
[26]   SYNTHESIS AND APPLICATION OF FLUORINE-CONTAINING HETEROCYCLES [J].
TANAKA, K .
JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 1990, 48 (01) :16-28
[27]   Synthesis of functionalized fluorine-containing trimethylsilylcarbodiimides [J].
D. V. Romanov ;
T. V. Strelkova ;
Yu. A. Strelenko ;
N. V. Vasil'ev .
Russian Chemical Bulletin, 1999, 48 :771-773
[28]   SYNTHESIS OF SOME FLUORINE-CONTAINING TRINITROBENZENES [J].
SHAW, GC ;
SEATON, DL .
JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (12) :5227-&
[29]   SYNTHESIS OF FLUORINE-CONTAINING ORGANOSILICON OLIGOMERS [J].
SAWADA, H ;
NAKAYAMA, M .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1991, (10) :677-678
[30]   Synthesis of Fluorine-Containing Exoalkylidene β-Lactams [J].
El Dine, Assaad Nasr ;
Gree, Danielle ;
Roisnel, Thierry ;
Caytan, Elsa ;
Hachem, Ali ;
Gree, Rene .
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 2016 (03) :556-561