SYNTHESIS OF FLUORINE-CONTAINING ISOSTERES OF SPHINGOSINE AS INACTIVATORS OF PROTEIN KINASE-C

被引:29
|
作者
KOZIKOWSKI, AP [1 ]
WU, JP [1 ]
机构
[1] UNIV PITTSBURGH,CHEVRON SCI CTR,DEPT BEHAV NEUROSCI,PITTSBURGH,PA 15260
关键词
D O I
10.1016/S0040-4039(00)97608-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Syntheses of isosteres of D-sphingosine in which either the primary or the secondary hydroxyl group of the parent compound has been replaced by a fluorine substituent are described. © 1990.
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页码:4309 / 4312
页数:4
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