Protein-Protein Interaction Analysis by Docking

被引：2

作者：

Fink, Florian ^{[1
]}

Ederer, Stephan ^{[1
]}

Gronwald, Wolfram ^{[1
]}

机构：

[1] Univ Regensburg, Inst Funct Gen, Josef Engert Str 9, D-93053 Regensburg, Germany

来源：

ALGORITHMS | 2009年 / 2卷 / 01期

关键词：

Protein-protein docking; verification of protein interactions; 3D protein structures;

D O I：

10.3390/a2010429

中图分类号：

TP18 [人工智能理论];

学科分类号：

081104 ; 0812 ; 0835 ; 1405 ;

摘要：

Based on a protein-protein docking approach we have developed a procedure to verify or falsify protein-protein interactions that were proposed by other methods such as yeast-2-hybrid assays. Our method currently utilizes intermolecular energies but can be expanded to incorporate additional terms such as amino acid based pair-potentials. We show some early results that demonstrate the general applicability of our approach.

引用

页码：429 / 436

页数：8

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