CORTICAL MECHANISMS MEDIATING ASTERIXIS

被引：32
作者：
ARTIEDA, J [1 ]
MURUZABAL, J [1 ]
LARUMBE, R [1 ]
DECASASOLA, CG [1 ]
OBESO, JA [1 ]
机构：
[1] UNIV NAVARRA,DEPT NEUROL,NEUROPHYSIOL SERV CLIN,CLIN UNIV,APDO 192,E-31080 PAMPLONA,SPAIN
来源：
MOVEMENT DISORDERS | 1992年 / 7卷 / 03期
关键词：
ASTERIXIS; CORTICAL ORIGIN; MYOCLONUS;
D O I：
10.1002/mds.870070304
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We describe a patient with chronic renal failure who suffered multifocal action-induced jerks. Electromyography (EMG) recorded the typical silence of asterixis. Back-averaging the EEG activity preceding the EMG silent periods in the forearm showed a biphasic wave antedating the asterixis by 23 ms. Somatosensory evoked potentials (SEPs) after median nerve stimulation were pathologically enlarged on both hemispheres. Brain-mapping of the biphasic wave preceding asterixis and the giant SEPs indicated a common origin in the sensorimotor cortex. This observation provides further documentation of a cortical origin for some types of asterixis in humans.
引用
收藏
页码：209 / 216
页数：8
相关论文
共 18 条
  • [1] Adams RD., Foley JM., The neurological changes in the more common types of severe liver disease, Trans Am Neurol Assoc, 74, pp. 217-219, (1949)
  • [2] Young RR, Shahani BT., Asterixis: one type of negative myoclonus, Adv Neurol, 43, pp. 137-156, (1986)
  • [3] Leavitt S, Tyler HR., Studies in asterixis, Arch Neurol, 10, pp. 360-368, (1964)
  • [4] Ugawa Y, Shimpo J, Hannen T., Physiological analysis of asterixis: silent period locked averaging, J Neurol Neurosurg Psychiatry, 52, pp. 89-93, (1989)
  • [5] Weinreb WH, Perry RJ, Jenkyn LR., Rhythmic alternating asterixis, J Neurol Neurosurg Psychiatry, 45, pp. 857-858, (1982)
  • [6] Marsden CD, Hallett M, Fahn S., The nosology and pathophysiology of myoclonus, Movement disorders, pp. 196-248, (1982)
  • [7] Obeso JA, Artieda J, Marsden CD., Different clinical presentations of myoclonus, Parkinson's disease and movement disorders, pp. 263-274, (1988)
  • [8] Hallett M, Chadwick D, Marsden CD., Cortical reflex myoclonus, Neurology, 29, pp. 1107-1125, (1979)
  • [9] Obeso JA, Rothwell J, Marsden CD., The spectrum of cortical myoclonus, Brain, 108, pp. 193-224, (1986)
  • [10] Santamaria J, Graus F, Martinez F., Asterixis en lesiones focales del sistema nervioso central, Rev Clin Espaãa, 168, pp. 37-39, (1983)
12