OXIDATIVE-METABOLISM OF HEXOBARBITAL IN HUMAN-LIVER - RELATIONSHIP TO POLYMORPHIC S-MEPHENYTOIN 4-HYDROXYLATION

被引：0

作者：

KNODELL, RG

DUBEY, RK

WILKINSON, GR

GUENGERICH, FP

机构：

[1] VANDERBILT UNIV,MED CTR,SCH MED,DEPT BIOCHEM,NASHVILLE,TN 37232

[2] VANDERBILT UNIV,MED CTR,SCH MED,DEPT PHARMACOL,NASHVILLE,TN 37232

[3] VANDERBILT UNIV,MED CTR,SCH MED,CTR MOLEC TOXICOL,NASHVILLE,TN 37232

来源：

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS | 1988年 / 245卷 / 03期

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：845 / 849

页数：5

共 40 条

[1] PHARMACOKINETICS OF (+)-HEXOBARBITONE, (-)-HEXOBARBITONE AND (+-]-HEXOBARBITONE IN MAN AFTER ORAL ADMINISTRATION
BREIMER, DD
VANROSSU.JM
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1973, 25 (09) : 762 - 764
[2] BREIMER DD, 1978, CLIN PHARMACOL THER, V24, P208
[3] BREIMER DD, 1975, CLIN PHARMACOL THER, V18, P433
[4] PHARMACOKINETICS OF ENANTIOMERS OF HEXOBARBITAL STUDIES IN SAME INTACT RAT AND IN SAME ISOLATED PERFUSED RAT-LIVER
BREIMER, DD
VANROSSU.JM
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1974, 26 (02) : 321 - 330
[5] IMMUNOQUANTIFICATION OF EPOXIDE HYDROLASE AND CYTOCHROME-P-450 ISOZYMES IN FETAL AND ADULT HUMAN-LIVER MICROSOMES
CRESTEIL, T
BEAUNE, P
KREMERS, P
CELIER, C
GUENGERICH, FP
LEROUX, JP
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1985, 151 (02): : 345 - 350
[6] DISTLERATH LM, 1985, J BIOL CHEM, V260, P9057
[7] CHARACTERIZATION OF A HUMAN-LIVER CYTOCHROME-P-450 INVOLVED IN THE OXIDATION OF DEBRISOQUINE AND OTHER DRUGS BY USING ANTIBODIES RAISED TO THE ANALOGOUS RAT ENZYME
DISTLERATH, LM
GUENGERICH, FP
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23): : 7348 - 7352
[8] GOODHART S, 1987, CLIN RES, V35, pA9
[9] GUENGERICH FP, 1986, J BIOL CHEM, V261, P5051
[10] PURIFICATION AND CHARACTERIZATION OF LIVER MICROSOMAL CYTOCHROMES-P-450 - ELECTROPHORETIC, SPECTRAL, CATALYTIC, AND IMMUNOCHEMICAL PROPERTIES AND INDUCIBILITY OF 8 ISOZYMES ISOLATED FROM RATS TREATED WITH PHENOBARBITAL OR BETA-NAPHTHOFLAVONE
GUENGERICH, FP
DANNAN, GA
WRIGHT, ST
MARTIN, MV
KAMINSKY, LS
[J]. BIOCHEMISTRY, 1982, 21 (23) : 6019 - 6030

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