Non-alcoholic fatty liver disease (NAFLD): a tale of fat and sugar?

被引：30
作者：
Longato, Lisa [1 ]
机构：
[1] UCL, Royal Free Hosp, Inst Liver & Digest Hlth, U3rd Floor,Rowland Hill St, London NW3 2PF, England
来源：
FIBROGENESIS & TISSUE REPAIR | 2013年 / 6卷
关键词：
Fructose; High-fat diet; High-fructose corn syrup; Mice; NAFLD; Non-alcoholic steatohepatitis; Rats; Western diet;
D O I：
10.1186/1755-1536-6-14
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The global diffusion of the so-called Western diet, which is enriched in fat and carbohydrates, such as fructose, has been proposed to be an underlying cause of the increased prevalence of metabolic conditions, including nonalcoholic fatty liver disease (NAFLD). This Smart Card summarizes the main metabolic and hepatic histological features of rodent models fed with diets combining high fat and fructose.
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