RNA FINGERPRINTING AND DIFFERENTIAL DISPLAY USING ARBITRARILY PRIMED PCR

被引：198

作者：

MCCLELLAND, M

MATHIEUDAUDE, F

WELSH, J

机构：

[1] M. McClelland, F. Mathieu-Daude and J. Welsh are in The California Institute of Biological Research, La Jolla, CA 92037

来源：

TRENDS IN GENETICS | 1995年 / 11卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0168-9525(00)89058-7

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

RNA fingerprinting by arbitrarily primed PCR can be used to detect and clone transcripts that are differentially, expressed between cells that have been subject to different environments or developmental programs. The method also allows atl estimate of tbe number of genes that are differentially expressed under various circumstances. When many experimental treatments are compared in parallel, intersecting regulatory pathways are reflected in genes that are perturbed by more than one treatment.

引用

页码：242 / 246

页数：5

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