MOLECULAR-CLONING OF A NEW TRANSFORMING GENE FROM A CHEMICALLY TRANSFORMED HUMAN CELL-LINE

被引：900

作者：

COOPER, CS

PARK, M

BLAIR, DG

TAINSKY, MA

HUEBNER, K

CROCE, CM

VANDEWOUDE, GF

机构：

[1] NCI, FREDERICK CANC RES FACIL, MOLEC ONCOL LAB, FREDERICK, MD 21701 USA

[2] WISTAR INST ANAT & BIOL, PHILADELPHIA, PA 19104 USA

[3] LITTON BIONET INC, BASIC RES PROGRAM, FREDERICK, MD 21701 USA

来源：

NATURE | 1984年 / 311卷 / 5981期

关键词：

D O I：

10.1038/311029a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Molecular cloning of the transforming gene from a chemically transformed human osteosarcoma-derived cell line enables the gene to be mapped to chromosome 7 (7p11.4-7qter) and by this criterion and by direct hybridization to be shown to be unrelated to known oncogenes.

引用

页码：29 / 33

页数：5

共 52 条

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