SPINAL-CORD INFARCTS DURING LONG-TERM INHIBITION OF NITRIC-OXIDE SYNTHASE IN RATS

被引：63
作者：
BLOT, S
ARNAL, JF
XU, Y
GRAY, F
MICHEL, JB
机构：
[1] INSERM, U367, F-75005 PARIS, FRANCE
[2] ECOLE VET ALFORT, MAISONS ALFORT, FRANCE
[3] INSERM, U153, PARIS, FRANCE
[4] HOP RAY POINCARE, GARCHES, FRANCE
来源：
STROKE | 1994年 / 25卷 / 08期
关键词：
HYPERTENSION; NITRIC OXIDE; SPINAL CORD; RATS;
D O I：
10.1161/01.STR.25.8.1666
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background and Purpose Chronic hypertension is a major predisposing factor for stroke in humans. It has recently been shown that long-term inhibition of nitric oxide synthase activity causes a gradual time-dependent increase in arterial blood pressure in rats. We used this new animal model of chronic hypertension to study the occurrence and spatial features of infarcts in the central nervous system.
引用
收藏
页码：1666 / 1673
页数：8
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