MOTIFS INVOLVED IN PROTEIN-PROTEIN INTERACTIONS

被引：10
|
作者：
SLINGSBY, C
BATEMAN, OA
SIMPSON, A
机构：
[1] Laboratory of Molecular Biology, Department of Crystallography, Birkbeck College, London, WCIE 7HX, Malet Street
来源：
MOLECULAR BIOLOGY REPORTS | 1993年 / 17卷 / 03期
关键词：
MOTIF; DOMAIN; INTERFACE; OLIGOMER; HELIX-BUNDLE; BETA-SHEET;
D O I：
10.1007/BF00986727
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Interactions between proteins are extremely variable. However, in the dimeric proteins comprised of regular motifs, interface interactions are similar to those that stabilize monomers. Additional stability is gained by converting loops within motifs or domains to linkers across interfaces. In multi-domain proteins, interactions can be greatly effected by the conformation of linkers between domains. Complex association of subunits, involving higher rotational symmetry or cubic symmetry, frequently involves motif sharing across interfaces. © 1993 Kluwer Academic Publishers.
引用
收藏
页码：185 / 195
页数：11
相关论文
共 50 条
  • [41] Visualizing protein-protein interactions involved in poly(ADP-ribose) metabolism
    Droit, A.
    Hunter, J.
    Cloutier, A. Picard
    Fillon, J.
    Poirier, G.
    MOLECULAR & CELLULAR PROTEOMICS, 2005, 4 (08) : S19 - S19
  • [42] Genetic assays to define and characterize protein-protein interactions involved in gene regulation
    Nickels, Bryce E.
    METHODS, 2009, 47 (01) : 53 - 62
  • [43] Protein-protein interactions define new pathways involved in the regulation of the dopamine transporter
    Torres, GE
    JOURNAL OF NEUROCHEMISTRY, 2004, 90 : 133 - 133
  • [44] Structural Insights into Protein-Protein Interactions Involved in Bacterial Cell Wall Biogenesis
    Laddomada, Federica
    Miyachiro, Mayara M.
    Dessen, Andrea
    ANTIBIOTICS-BASEL, 2016, 5 (02):
  • [45] The amino terminus of bacteriophage λ integrase is involved in protein-protein interactions during recombination
    Jessop, L
    Bankhead, T
    Wong, D
    Segall, AM
    JOURNAL OF BACTERIOLOGY, 2000, 182 (04) : 1024 - 1034
  • [46] Protein-protein interactions involved in chemotaxis of Epulopiscium sp. type b
    Faughnan, Patrick
    Piefer, Andrew
    FASEB JOURNAL, 2014, 28 (01):
  • [47] Aquaporin Protein-Protein Interactions
    Roche, Jennifer Virginia
    Tornroth-Horsefield, Susanna
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (11)
  • [48] Interference with protein-protein interactions involved in protease-inhibitor complex fromation
    van Zoelen, DJ
    Egmond, MR
    Pieters, RJ
    Liskamp, RMJ
    BIOPOLYMERS, 2005, 80 (04) : 514 - 514
  • [49] Dissecting Protein-Protein Interactions
    Sundberg, Eric J.
    GENETIC ENGINEERING & BIOTECHNOLOGY NEWS, 2009, 29 (06): : 34 - 35
  • [50] Measuring protein-protein interactions
    Lakey, JH
    Raggett, EM
    CURRENT OPINION IN STRUCTURAL BIOLOGY, 1998, 8 (01) : 119 - 123
12345