PLASMA PEROXYL RADICAL-TRAPPING CAPACITY IN SEVERE PREECLAMPSIA IS STRONGLY RELATED TO URIC-ACID

被引：18

作者：

UOTILA, J ^{[1
]}

METSAKETELA, T ^{[1
]}

TUIMALA, R ^{[1
]}

机构：

[1] TAMPERE UNIV,INST BIOMED SCI,SF-33101 TAMPERE,FINLAND

来源：

CLINICAL AND EXPERIMENTAL HYPERTENSION PART B-HYPERTENSION IN PREGNANCY | 1992年 / 11卷 / 01期

关键词：

D O I：

10.3109/10641959209031034

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The total peroxyl radical-trapping antioxidant parameter (TRAP) of plasma from nine patients suffering from severe preeclampsia was compared with that from nine control patients sharing the same weeks of pregnancy. Measurement of TRAP was by a new chemiluminescent method. The mean TRAP in preeclamptic patients was 1288 +/- 110 mumol/l and in control patients 970 +/- 153 mumol/l (p<0.001). TRAP was highly correlated with plasma uric acid (r=0.86), and 91% of the increase in TRAP was due to increase in uric acid, which raises a question of the possible antioxidative role of uric acid in preeclampsia.

引用

页码：71 / 80

页数：10

共 17 条

[1] URIC-ACID PROVIDES AN ANTIOXIDANT DEFENSE IN HUMANS AGAINST OXIDANT-CAUSED AND RADICAL-CAUSED AGING AND CANCER - A HYPOTHESIS [J].