MELANOTIC NEUROECTODERMAL TUMOR OF INFANCY - A MOLECULAR APPROACH TO DIAGNOSIS - CASE-REPORT

被引：31

作者：

NITTA, T ^{[1
]}

ENDO, T ^{[1
]}

TSUNODA, A ^{[1
]}

KADOTA, Y ^{[1
]}

MATSUMOTO, T ^{[1
]}

SATO, K ^{[1
]}

机构：

[1] JUNTENDO UNIV,SCH MED,DEPT PATHOL,TOKYO 113,JAPAN

来源：

JOURNAL OF NEUROSURGERY | 1995年 / 83卷 / 01期

关键词：

MELANOTIC NEUROECTODERMAL TUMOR; POLYMERASE CHAIN REACTION; MELANOMA; MELANOTRANSFERRIN;

D O I：

10.3171/jns.1995.83.1.0145

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A case of melanotic neuroectodermal tumor of infancy arising from the transverse sinus is presented. The tumor was located on the outer surface of the dura and extended extracranially through the occipitomastoid suture. Two cell populations were observed: pigmented melanocyte-like cells and small neuroblast-like cells. Ultrastructural analysis revealed epithelial tumor cells and melanosomes at various stages. Expression of melanotransferrin messenger RNA transcripts within the tumor tissue was observed using a reverse transcriptase-polymerase chain reaction method in addition to immunohistological studies. The positive expression of melanotransferrin confirmed that this melanotic neuroectodermal tumor was derived from neural crest cells.

引用

页码：145 / 148

页数：4

共 34 条

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[2] MELANOTIC NEUROECTODERMAL TUMOR OF INFANCY - MR FINDINGS AND A REVIEW OF THE LITERATURE [J].