CHRONIC HYPERGLYCEMIA IS ASSOCIATED WITH IMPAIRED GLUCOSE INFLUENCE ON INSULIN-SECRETION - A STUDY IN NORMAL RATS USING CHRONIC INVIVO GLUCOSE INFUSIONS

被引：322

作者：

LEAHY, JL ^{[1
]}

COOPER, HE ^{[1
]}

DEAL, DA ^{[1
]}

WEIR, GC ^{[1
]}

机构：

[1] BRIGHAM & WOMENS HOSP,BOSTON,MA 02115

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1986年 / 77卷 / 03期

关键词：

D O I：

10.1172/JCI112389

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：908 / 915

页数：8

共 35 条

[1] SENSITIVE, PRECISE RADIOIMMUNOASSAY OF SERUM-INSULIN RELYING ON CHARCOAL SEPARATION OF BOUND AND FREE HORMONE MOIETIES [J].

ALBANO, JDM ;

EKINS, RP ;

TURNER, RC ;

MARITZ, G .

ACTA ENDOCRINOLOGICA, 1972, 70 (03) :487-+

[2] INSULIN THERAPY IN OBESE, NON-INSULIN-DEPENDENT DIABETES INDUCES IMPROVEMENTS IN INSULIN ACTION AND SECRETION THAT ARE MAINTAINED FOR 2 WEEKS AFTER INSULIN WITHDRAWAL [J].

ANDREWS, WJ ;

VASQUEZ, B ;

NAGULESPARAN, M ;

KLIMES, I ;

FOLEY, J ;

UNGER, R ;

REAVEN, GM .

DIABETES, 1984, 33 (07) :634-642

[3] PARTIAL PANCREATECTOMY IN THE RAT AND SUBSEQUENT DEFECT IN GLUCOSE-INDUCED INSULIN RELEASE [J].

BONNERWEIR, S ;

TRENT, DF ;

WEIR, GC .

JOURNAL OF CLINICAL INVESTIGATION, 1983, 71 (06) :1544-1553

[4] RESPONSES OF NEONATAL RAT ISLETS TO STREPTOZOTOCIN - LIMITED B-CELL REGENERATION AND HYPERGLYCEMIA [J].

BONNERWEIR, S ;

TRENT, DF ;

HONEY, RN ;

WEIR, GC .

DIABETES, 1981, 30 (01) :64-69

[5]

BRODSKY GM, 1975, ENDOKRINOLOGIE, V66, P46

[6] RELEASE OF LARGE AMOUNTS OF NORADRENALINE FROM ISOLATED PERFUSED CANINE PANCREAS DURING GLUCOSE DEPRIVATION [J].

CHRISTENSEN, NJ ;

IVERSEN, J .

DIABETOLOGIA, 1973, 9 (05) :396-399

[7] ISLET CHANGES INDUCED BY HYPERGLYCEMIA IN RATS - EFFECT OF INSULIN OR CHLORPROPAMIDE THERAPY [J].

CLARK, A ;

BOWN, E ;

KING, T ;

VANHEGAN, RI ;

TURNER, RC .

DIABETES, 1982, 31 (04) :319-325

[8] GLUCOSE OXIDATION (14-CO2 PRODUCTION) AND INSULIN-SECRETION BY PANCREATIC-ISLETS ISOLATED FROM HYPERGLYCEMIC AND NORMOGLYCEMIC RATS [J].

COLE, EH ;

LOGOTHETOPOULOS, J .

DIABETES, 1974, 23 (05) :469-473

[9]

DIMITRIADIS G, 1985, DIABETOLOGIA, V28, P63

[10] EFFECT OF CONTINUOUS INSULIN INFUSION WITH AN IMPLANTABLE 7-DAY MINIPUMP IN THE DIABETIC CHINESE-HAMSTER [J].

FRANKEL, BJ ;

SCHMID, FG ;

GRODSKY, GM .

ENDOCRINOLOGY, 1979, 104 (05) :1532-1539

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