AN IMMUNOREACTIVE XANTHINE-OXIDASE PROTEIN-POSSESSING XANTHINURIA AND HER FAMILY

被引：4

作者：

YAMAMOTO, T ^{[1
]}

MORIWAKI, Y ^{[1
]}

SUDA, M ^{[1
]}

TAKAHASHI, S ^{[1
]}

HADA, T ^{[1
]}

NANAHOSHI, M ^{[1
]}

AGBEDANA, EO ^{[1
]}

HIGASHINO, K ^{[1
]}

机构：

[1] KINKI CENT HOSP MUTUAL AID ASSOC PUBL SCH TEACHERS,DEPT INTERNAL MED,ITAMI,HYOGO 663,JAPAN

来源：

CLINICA CHIMICA ACTA | 1992年 / 208卷 / 1-2期

关键词：

XANTHINE OXIDASE; XANTHINURIA; XANTHINE OXIDASE PROTEIN;

D O I：

10.1016/0009-8981(92)90025-L

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The presence of immunoreactive xanthine oxidase protein was proven in a xanthinuric patient, using a polyclonal antibody against xanthine oxidase. The antibody was raised against purified human liver xanthine oxidase in a rabbit. Double immunodiffusion method demonstrated the existence of an immunologically reactive xanthine oxidase which did not possess xanthine oxidase activity. In addition, urinary excretion of oxypurines in the patient and her family was investigated. The results indicated that a brother and a sister had xanthinuria.

引用

页码：93 / 98

页数：6

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