Biocatalyst behaviour in low-water systems

被引：178
作者：
Bell, G
Halling, PJ
Moore, BD
Partridge, J
Rees, DG
机构：
[1] UNIV STRATHCLYDE, DEPT BIOSCI & BIOTECHNOL, GLASGOW G1 1XW, LANARK, SCOTLAND
[2] UNIV STRATHCLYDE, DEPT PURE & APPL CHEM, GLASGOW G1 1XW, LANARK, SCOTLAND
来源：
TRENDS IN BIOTECHNOLOGY | 1995年 / 13卷 / 11期
基金：
英国生物技术与生命科学研究理事会;
关键词：
D O I：
10.1016/S0167-7799(00)89004-6
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
An improving understanding of the parameters that affect biocatalyst activity, specificity and stability in low-water non-aqueous media make reliable predictions about the behaviour of such systems increasingly feasible, Here, we discuss some of the key factors, such as control of water activity, and the effects of solvent on K-m and protein-ionization state, that must be addressed in order to obtain predictable results.
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页码：468 / 473
页数：6
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