BLEOMYCIN SCLEROTHERAPY IN PATIENTS WITH CONGENITAL LYMPHATIC MALFORMATION IN THE HEAD AND NECK

被引：50

作者：

SUNG, MW

CHANG, SO

CHOI, JH

KIM, JY

机构：

[1] SEOUL NATL UNIV,COLL MED,DEPT OTOLARYNGOL,SEOUL,SOUTH KOREA

[2] SEOUL NATL UNIV,COLL MED,DEPT PEDIAT,SEOUL,SOUTH KOREA

来源：

AMERICAN JOURNAL OF OTOLARYNGOLOGY | 1995年 / 16卷 / 04期

关键词：

D O I：

10.1016/0196-0709(95)90149-3

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Congenital lymphatic malformations of the head and neck often present challenging problems to the otolaryngologist-head and neck surgeon. Although surgical excision was agreed to be the treatment of choice for this disease, the infiltrating nature of lymphatic channels often increases the frequency of operative complications and recurrences of this lesion. Purpose: Bleomycin sclerotherapy was attempted to avoid surgical risk and to cure this lesion. Materials and Methods: Clinical findings and treatment results were reviewed for patients with congenital lymphatic malformation and treated by bleomycin sclerotherapy. Results: Bleomycin sclerotherapy was a very effective therapeutic alternative. The best results were seen in cystic type I lesions in younger patients. Conclusions: Bleomycin sclerotherapy is a useful medical alternative, and we believe that it should be attempted before excision of the lesion. Copyright (C) 1995 by W.B. Saunders Company

引用

页码：236 / 241

页数：6

共 23 条

[1]

Ricciardelli, Richardson, Cervicofacial cytic hygroma: Patterns of recurrence and management of the difficult case, Arch Otolaryngol Head Neck Surg, 117, pp. 546-553, (1991)

[2]

Emery, Bailey, Evans, Cystic hygroma of the head and neck: A review of 37 cases, J Laryngol Otol, 98, pp. 613-619, (1984)

[3]

Hellmann, Myer, Prenger, Therapeutic alternatives in the treatment of life-threatening vasoformative tumors, Am J Otolaryngol, 13, pp. 48-53, (1992)

[4]

Okada, Kubota, Fukuzawa, Et al., Injection of bleomycin as a primary therapy of cystic lymphagioma, J Pediatr Surg, 27, pp. 440-443, (1992)

[5]

Hancock, St-Vil, Luks, Et al., Complications of lymphangiomas in children, J Pediatr Surg, 27, pp. 220-226, (1992)

[6]

Dickerhoff, Bode, Cyclophosphamide in nonresectable cystic hygroma, Lancet, 335, pp. 1474-1475, (1990)

[7]

Seashore, Gardiner, Ariyan, Management of giant cystic hygromas in infants, Am J Surg, 149, pp. 459-466, (1985)

[8]

Tanigawa, Shimomatsuya, Takahashi, Et al., Treatment of cystic hygroma and lymphangioma with the use of bleomycin fat emulsion, Cancer, 60, pp. 741-749, (1987)

[9]

Yura, Hashimoto, Nakamura, Et al., Bleomycin treatment for cystic hygroma in children, Arch Jpn Chir, 46, pp. 607-612, (1977)

[10]

McGill, Mulliken, Vascular anomalies of the head and neck, Otolaryngology-Head and Neck Surgery, 1, pp. 333-346, (1993)

← 1 2 3 →