ALKALINE-PHOSPHATASE AND PHOSPHOAMINO ACID-PHOSPHATASES IN NORMAL AND CANCEROUS TISSUES OF THE HUMAN LARYNX

被引：6

作者：

HAMMOND, KD ^{[1
]}

MOHAMED, E ^{[1
]}

GREGOR, RT ^{[1
]}

机构：

[1] UNIV WITWATERSRAND,SCH MED,DEPT OTOLARYNGOL,JOHANNESBURG 2001,SOUTH AFRICA

来源：

BIOCHEMICAL MEDICINE AND METABOLIC BIOLOGY | 1990年 / 43卷 / 01期

关键词：

D O I：

10.1016/0885-4505(90)90010-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The activities of alkaline phosphatase and phosphoamino acid phosphatases were measured in normal and cancerous regions of the human larynx. For each larynx, alkaline phosphatase and phosphotyrosine phosphatase activities were higher in the tumor than in the corresponding normal tissue. Phosphothreonine and phosphoserine phosphatase activities were relatively low and there were no consistent trends. The increased alkaline phosphatase activity in the tumors supports histological observations that ossification of cartilage seems to occur at the site of invasion; the phosphatase acting on phosphotyrosine could serve as a regulator of cell differentiation during tumorigenesis. © 1990.

引用

页码：75 / 79

页数：5

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