HALOPERIDOL DETERMINATION IN SERUM AND CEREBROSPINAL-FLUID USING GAS-LIQUID-CHROMATOGRAPHY WITH NITROGEN PHOSPHORUS DETECTION - APPLICATION TO PHARMACOKINETIC STUDIES

被引：19
作者：
ABERNETHY, DR
GREENBLATT, DJ
OCHS, HR
WILLIS, CR
MILLER, DD
SHADER, RI
机构：
[1] TUFTS UNIV,SCH MED,DEPT PSYCHIAT,DIV CLIN PHARMACOL,BOSTON,MA 02111
[2] TUFTS UNIV,SCH MED,DEPT MED,BOSTON,MA 02111
[3] NEW ENGLAND MED CTR HOSP,BOSTON,MA 02111
[4] UNIV BONN,MED KLIN,D-5300 BONN,FED REP GER
[5] CASE WESTERN RESERVE UNIV,SCH MED,CLEVELAND,OH 44106
[6] CASE WESTERN RESERVE UNIV HOSP,CLEVELAND,OH 44106
来源：
JOURNAL OF CHROMATOGRAPHY | 1984年 / 307卷 / 01期
关键词：
D O I：
10.1016/S0378-4347(00)84087-6
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
引用
收藏
页码：194 / 199
页数：6
相关论文
共 14 条
[1]   EFFECTS OF DESMETHYLDIAZEPAM ON DIAZEPAM KINETICS - A STUDY OF EFFECTS OF A METABOLITE ON PARENT DRUG DISPOSITION [J].
ABERNETHY, DR ;
GREENBLATT, DJ .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 1981, 29 (06) :757-761
[2]   RAPID AND SENSITIVE METHOD FOR DETERMINATION OF HALOPERIDOL IN HUMAN SAMPLES USING NITROGEN-PHOSPHORUS SELECTIVE DETECTION [J].
BIANCHETTI, G ;
MORSELLI, PL .
JOURNAL OF CHROMATOGRAPHY, 1978, 153 (01) :203-209
[3]   RADIORECEPTOR ASSAY OF HALOPERIDOL TISSUE-LEVELS IN THE RAT [J].
COHEN, BM ;
HERSCHEL, M ;
MILLER, E ;
MAYBERG, H ;
BALDESSARINI, RJ .
NEUROPHARMACOLOGY, 1980, 19 (07) :663-668
[4]   DETERMINATION OF ANTIPSYCHOTIC-DRUGS BY GAS-LIQUID-CHROMATOGRAPHY WITH A NITROGEN DETECTOR USING A SIMPLE ACETYLATION TECHNIQUE [J].
DEKIRMENJIAN, H ;
JAVAID, JI ;
DUSLAK, B ;
DAVIS, JM .
JOURNAL OF CHROMATOGRAPHY, 1978, 160 (01) :291-296
[5]  
DIMASCIO A, 1972, BUTYROPHENONES PSYCH
[6]   GAS-CHROMATOGRAPHIC METHOD FOR DETERMINING HALOPERIDOL - SENSITIVE PROCEDURE FOR STUDYING SERUM CONCENTRATION AND PHARMACOKINETICS OF HALOPERIDOL IN PATIENTS [J].
FORSMAN, A ;
MARTENSSON, E ;
NYBERG, G ;
OHMAN, R .
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1974, 286 (02) :113-124
[7]  
FRANKLIN M, 1980, CLIN CHEM, V136, P1367
[8]   ENTRY OF DIAZEPAM AND ITS MAJOR METABOLITE INTO CEREBROSPINAL-FLUID [J].
GREENBLATT, DJ ;
OCHS, HR ;
LLOYD, BL .
PSYCHOPHARMACOLOGY, 1980, 70 (01) :89-93
[9]   HALOPERIDOL KINETICS AFTER ORAL AND INTRAVENOUS DOSES [J].
HOLLEY, FO ;
MAGLIOZZI, JR ;
STANSKI, DR ;
LOMBROZO, L ;
HOLLISTER, LE .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 1983, 33 (04) :477-484
[10]  
KORPI ER, 1983, CLIN CHEM, V29, P624
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