CONTROLLING CARDIAC CHAOS

被引：708
作者：
GARFINKEL, A
SPANO, ML
DITTO, WL
WEISS, JN
机构：
[1] USN,CTR SURFACE WARFARE,SILVER SPRING,MD 20903
[2] COLL WOOSTER,DEPT PHYS,WOOSTER,OH 44691
[3] UNIV CALIF LOS ANGELES,DEPT MED CARDIOL,LOS ANGELES,CA 90024
来源：
SCIENCE | 1992年 / 257卷 / 5074期
关键词：
D O I：
10.1126/science.1519060
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The extreme sensitivity to initial conditions that chaotic systems display makes them unstable and unpredictable. Yet that same sensitivity also makes them highly susceptible to control, provided that the developing chaos can be analyzed in real time and that analysis is then used to make small control interventions. This strategy has been used here to stabilize cardiac arrhythmias induced by the drug ouabain in rabbit ventricle. By administering electrical stimuli to the heart at irregular times determined by chaos theory, the arrhythmia was converted to periodic beating.
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收藏
页码：1230 / 1235
页数：6
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