CIS-1,3,4,6,7,11B-HEXAHYDRO-2-METHYL-7-PHENYL-2H-PYRAZINO[2,1-A]ISOQUINOLINE - A NEW ATYPICAL ANTIDEPRESSANT

被引：21

作者：

GRIFFITH, RC ^{[1
]}

GENTILE, RJ ^{[1
]}

ROBICHAUD, RC ^{[1
]}

FRANKENHEIM, J ^{[1
]}

机构：

[1] PENNWALT CORP,DEPT PHARMACOL,DIV PHARMACEUT,ROCHESTER,NY 14603

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1984年 / 27卷 / 08期

关键词：

D O I：

10.1021/jm00374a011

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：995 / 1003

页数：9

共 15 条

[1] DEVELOPMENT OF BETA-ADRENERGIC-RECEPTOR SUBSENSITIVITY BY ANTIDEPRESSANTS [J].

BANERJEE, SP ;

KUNG, LS ;

RIGGI, SJ ;

CHANDA, SK .

NATURE, 1977, 268 (5619) :455-456

[2] N-DEMETHYLATION OF MORPHINE AND CODEINE USING METHYL CHLOROFORMATE [J].

BRINE, GA ;

BOLDT, KG ;

HART, CK ;

CARROLL, FI .

ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1976, 8 (03) :103-106

[3] EFFECTS OF ANTI-DEPRESSANTS AND RELATED DRUGS ON THE QUANTITATIVELY ANALYZED EEGS OF BEAGLES [J].

FRANKENHEIM, J .

DRUG DEVELOPMENT RESEARCH, 1982, 2 (02) :197-213

[4] A PROTEIN BINDING ASSAY FOR ADENOSINE 3'-5'-CYCLIC MONOPHOSPHATE [J].

GILMAN, AG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1970, 67 (01) :305-&

[5]

HITE G, UNPUB ACTA CRYSTALLO

[6]

ITIL TM, 1972, CURR THER RES CLIN E, V14, P395

[7] BRAIN HISTAMINE RECEPTORS AS TARGETS FOR ANTIDEPRESSANT DRUGS [J].

KANOF, PD ;

GREENGARD, P .

NATURE, 1978, 272 (5651) :329-333

[8]

LEONARD JJ, 1949, J AM CHEM SOC, V71, P3405

[9] SYNTHESIS AND STEREOCHEMISTRY OF 7-PHENYL-2-PROPIONANILIDOBENZO[A]QUINOLIZIDINE DERIVATIVES - STRUCTURAL PROBES OF FENTANYL ANALGESICS [J].

MARYANOFF, BE ;

MCCOMSEY, DF ;

TAYLOR, RJ ;

GARDOCKI, JF .

JOURNAL OF MEDICINAL CHEMISTRY, 1981, 24 (01) :79-88

[10]

Riebsomer J. L., 1950, J ORG CHEM, V15, P68

← 1 2 →