Aims: To evaluate the effect of cochlear implant (CI) on quality of life (QoL), quality of hearing (QoH), and working in patients with single-sided deafness (SSD). Methods: Using specific questionnaires, we measured QoL, QoH, and working performance in seven SSD patients scheduled for CI surgery of the affected ear. Sound localization and speech perception in noise were also assessed. All questionnaires and tests were performed before the CI surgery and at six and 12 months after CI activation. Results: The QoL, QoH, sound localization, and speech perception in noise improved statistically significantly after the CI. Communication with co-workers became easier, and the patients were less fatigued after the working day. Conclusions: CI clearly improves QoL, QoH, and working performance in patients with SSD. (C) 2015 S. Karger AG, Basel