Autologous Bone Marrow Transplantation for Polymyositis Combined with Myasthenia Gravis and Aplastic Anemia: A Case Report

被引：4

作者：

Mitsumune, Sho ^{[1
]}

Manabe, Yasuhiro ^{[1
]}

Yunoki, Taijun ^{[1
]}

Kono, Shyoichiro ^{[1
]}

Aoyama, Kazutoshi ^{[2
]}

Shinno, Yoko ^{[3
]}

Narai, Hisashi ^{[1
]}

Abe, Koji ^{[4
]}

机构：

[1] Natl Hosp Org Okayama Med Ctr, Dept Neurol, Okayama, Japan

[2] Natl Hosp Org Okayama Med Ctr, Dept Hematol, Okayama, Japan

[3] Natl Hosp Org Okayama Med Ctr, Clin Lab, Okayama, Japan

[4] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Neurol, Okayama, Japan

来源：

CASE REPORTS IN NEUROLOGY | 2018年 / 10卷 / 01期

关键词：

Polymyositis; Myasthenia gravis; Aplastic anemia; Bone marrow transplantation;

D O I：

10.1159/000488476

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This is the first report about a patient with concomitant polymyositis (PM), myasthenia gravis (MG), and aplastic anemia (AA). A 54-year-old male developed myalgia and muscle weakness, which gradually progressed over 2 months. He was persistently affected by MG and AA. Brachium magnetic resonance imaging showed increased signal intensity in the left triceps and deltoid muscles on short tau inversion recovery images. A muscle biopsy examination revealed perifascicular atrophication and inflammatory myopathy. We diagnosed the patient with PM combined with MG and AA. He was successfully treated with an autologous bone marrow transplantation (BMT). The present case suggests that BMT is a therapeutic option for PM, MG, and AA. (C) 2018 The Author(s) Published by S. Karger AG, Basel

引用

页码：108 / 111

页数：4

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