CALCITONIN GENE-RELATED PEPTIDE IN THE DEVELOPING MOUSE OLFACTORY SYSTEM

被引：15

作者：

BAKER, H

机构：

[1] Cornell University Medical College, The Burke Rehabilitation Center, White Plains

来源：

DEVELOPMENTAL BRAIN RESEARCH | 1990年 / 54卷 / 02期

关键词：

Olfactory epithelium; Olfactory marker protein; Phenotypic expression; Rodent; Tyrosine hydroxylase;

D O I：

10.1016/0165-3806(90)90154-Q

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The development of calcitonin gene-related peptide (CGRP) was investigated in the mouse olfactory system. The peptide was not found in olfactory receptor neurons in embryos examined from gestational day 13 (E13) to E18 but was present in other brain regions and in peripheral tissues. At E18, CGRP-immunoreactive fibers, presumably of trigeminal, not olfactory receptor cell, origin were observed within the lamina propria. These data suggest that in vivo CGRP does not act through olfactory receptor neurons to regulate phenotypic expression in the olfactory bulb. © 1990.

引用

页码：295 / 298

页数：4

共 14 条

[1] ALTERNATIVE RNA PROCESSING IN CALCITONIN GENE-EXPRESSION GENERATES MESSENGER-RNAS ENCODING DIFFERENT POLYPEPTIDE PRODUCTS [J].