AGGRESSIVE OLIGODENDROGLIOMA - A CHEMOSENSITIVE TUMOR

被引：100
作者：
CAIRNCROSS, JG
GEORGE, ED
MACDONALD, DR
RAMSAY, DA
机构：
[1] UNIV WESTERN ONTARIO,DEPT CLIN NEUROL SCI,LONDON N6A 3K7,ONTARIO,CANADA
[2] UNIV WESTERN ONTARIO,DEPT ONCOL,LONDON N6A 3K7,ONTARIO,CANADA
[3] UNIV WESTERN ONTARIO,DEPT PATHOL,LONDON N6A 3K7,ONTARIO,CANADA
[4] VICTORIA HOSP,LONDON N6A 4G5,ONTARIO,CANADA
来源：
NEUROSURGERY | 1992年 / 31卷 / 01期
关键词：
AGGRESSIVE TUMORS; ANAPLASTIC TUMORS; CHEMOTHERAPY; NITROSOUREAS; OLIGODENDROGLIOMA; PROCARBAZINE; RESPONSE TO TREATMENT;
D O I：
10.1227/00006123-199207000-00011
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
AGGRESSIVE OLIGODENDROGLIOMAS, tumors that are symptomatic, enlarging, enhancing, and usually but not always anaplastic, respond to chemotherapy. We have observed responses to chemotherapy in 18 of 19 consecutively treated patients with newly diagnosed or recurrent aggressive oligodendrogliomas. A regimen of procarbazine, CCNU (lomustine), and vincristine (PCV) is predictably effective, but other drugs have anti-oligodendroglioma activity. Cooperative group trials will be necessary to determine the most effective drug, or combination of drugs, and to explore fully the role of chemotherapy in the treatment of this uncommon glioma. (Neurosurgery 31:78 82, 1992)
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页码：78 / 82
页数：5
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