CYCLIN-B IS ASSOCIATED WITH CENTROSOMES IN DROSOPHILA MITOTIC CELLS

被引：17

作者：

DEBEC, A

MONTMORY, C

机构：

[1] Groupe de Génetique Cellulaire et Moléculaire, Unite Associée, CNRS 1135, 75005 Paris, 7, Quai Saint-Bernard

来源：

BIOLOGY OF THE CELL | 1992年 / 75卷 / 02期

关键词：

CYCLIN-B; CENTROSOME; CENTRIOLES; DROSOPHILA;

D O I：

10.1016/0248-4900(92)90131-J

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have studied by way of confocal laser scanning microscopy the subcellular localization of cyclin B in Drosophila-cultured cells and report here evidence that a part of the cyclin B cell pool is closely associated with the centrosome. This cyclin B centrosomal signal is strong in prophase and metaphase but disappears during anaphase. Moreover, the signal is absent in the acentriolar Drosophila cell line 1182-4. These results put forward additional arguments suggesting that the centrosome plays an important role in the control of the cell cycle.

引用

页码：121 / 126

页数：6

共 40 条

[1] P34CDC2 IS LOCATED IN BOTH NUCLEUS AND CYTOPLASM - PART IS CENTROSOMALLY ASSOCIATED AT G2/M AND ENTERS VESICLES AT ANAPHASE [J].