REPRODUCIBILITY OF RESTING CEREBRAL BLOOD-FLOW MEASUREMENTS WITH H215O POSITRON EMISSION TOMOGRAPHY IN HUMANS

被引：67
作者：
MATTHEW, E
ANDREASON, P
CARSON, RE
HERSCOVITCH, P
PETTIGREW, K
COHEN, R
KING, C
JOHANSON, CE
PAUL, SM
机构：
[1] NIMH,NEUROSCI BRANCH,CLIN BRAIN IMAGING SECT,CEREBRAL BLOOD FLOW & METAB LAB,BETHESDA,MD 20892
[2] NIMH,DEPT NUCL MED,BETHESDA,MD 20892
[3] NIMH,DIV EPIDEMIOL & SERV RES,BETHESDA,MD 20892
[4] UNIFORMED SERV UNIV HLTH SCI,DEPT PSYCHIAT,BETHESDA,MD 20814
来源：
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM | 1993年 / 13卷 / 05期
关键词：
H215O POSITRON EMISSION TOMOGRAPHY; NORMALIZATION OF DATA; REGIONS OF INTEREST; REPRODUCIBILITY OF MEASUREMENT; RESTING CEREBRAL BLOOD FLOW;
D O I：
10.1038/jcbfm.1993.95
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Two consecutive measurements of resting CBF were carried out in normal volunteers (n = 25) using (H2O)-O-15 positron emission tomography. Absolute whole-brain blood flow (WBBF; ml 100 g-1 min-1, mean +/- SD) for the first (40.3 +/- 6.4) and second (39.3 +/- 6.5) measurements was not significantly different (mean % difference 2.3 +/- 8.7). Analysis of regions of interest showed no significant differences in absolute regional CBF (rCBF) and normalized (rCBF/WBBF) rCBF. Left-right differences were also not significant. These data demonstrate the reproducibility of resting CBF measurements in normal humans.
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收藏
页码：748 / 754
页数：7
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