CHRONIC TREATMENT WITH VASOPRESSIN ANALOGS ALTERS AFFINITY OF VASOPRESSIN RECEPTORS IN THE SEPTUM AND AMYGDALA OF THE RAT-BRAIN

被引：12
|
作者：
SWANK, MW
DORSA, DM
机构：
[1] VET ADM MED CTR, CTR GERIATR RES EDUC & CLIN 182B, 1660 S COLUMBIAN WAY, SEATTLE, WA 98108 USA
[2] UNIV WASHINGTON, SCH MED, DEPT PSYCHOL, SEATTLE, WA 98105 USA
[3] UNIV WASHINGTON, SCH MED, DEPT PHYSIOL & BIOPHYS, SEATTLE, WA 98105 USA
[4] UNIV WASHINGTON, SCH MED, DEPT PHARMACOL, SEATTLE, WA 98105 USA
[5] UNIV WASHINGTON, SCH MED, DEPT MED, SEATTLE, WA 98105 USA
来源：
BRAIN RESEARCH | 1991年 / 544卷 / 02期
关键词：
VASOPRESSIN RECEPTOR; BRAIN; ANTAGONIST; ACCUREL COLLOIDION DEVICE;
D O I：
10.1016/0006-8993(91)90077-9
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Accurel devices were used to administer AVP or AVP-antagonist into the lateral ventricle of the rat brain for 7 days. Neither AVP nor antagonist altered total binding site concentration in either septum or amygdala. However, treatment with antagonist caused a marked decrease in the affinity of the receptor for agonist in both the septum and amygdala.
引用
收藏
页码：342 / 344
页数：3
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