FAMILIAL OCCURRENCE OF TELANGIECTATIC OSTEOSARCOMA - COUSIN CASES

被引：15

作者：

NISHIDA, J

ABE, M

SHIRAISHI, H

SHIMAMURA, T

TAMURA, G

SATOH, T

EHARA, S

机构：

[1] Departments of Orthopedic Surgery, School of Medicine, Iwate Medical University, Morioka

[2] Departments of Pathology, School of Medicine, Iwate Medical University, Morioka

[3] Center for Radiological Science, School of Medicine, Iwate Medical University, Morioka

来源：

JOURNAL OF PEDIATRIC ORTHOPAEDICS | 1994年 / 14卷 / 01期

关键词：

COUSIN CASES; FAMILIAL OSTEOSARCOMA; TELANGIECTATIC OSTEOSARCOMA;

D O I：

10.1097/01241398-199401000-00023

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Familial occurrence of osteosarcoma is rare. We report cousin cases, an 11-year-old girl and an 8-year-old boy with telangiectatic osteosarcoma. The tumors occurred in the metaphysis of the distal tibia and the lamina of thoracic vertebra. The local behaviors appeared aggressive, but the clinical courses were relatively indolent in both cases. The histologic features were similar, showing anaplastic tumor cells producing osteoid and proliferation of blood cavities. Clustering of malignancies within a family suggests the presence of a genetic factor.

引用

页码：119 / 122

页数：4

共 23 条

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