GLAUCOMATOUS OPTIC NEUROPATHY CAUSES SENSITIVITY LOSS TO LIGHT OFFSETS IN THE VISUAL-FIELD

被引：0

作者：

MUTLUKAN, E ^{[1
]}

机构：

[1] UNIV GLASGOW, TENNENT INST OPHTHALMOL, GLASGOW G12 8QQ, SCOTLAND

来源：

NEUROREPORT | 1993年 / 4卷 / 10期

关键词：

OPTIC NEUROPATHY; PARALLEL PATHWAYS; OFF-PATHWAY; ON-PATHWAY; GLAUCOMA; CENTRAL VISION; VISUAL FIELD; PERIMETRY; MAGNOCELLULAR SYSTEM; NEUROOPHTHALMOLOGY;

D O I：

暂无

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

THE functional integrity of the 'on' and 'off' neurovisual pathways has been examined in the central visual fields of normal (n = 13), glaucomatous (n = 21) and ocular hypertensive (n = 21) individuals. The detection thresholds to light increments (onsets = bright spots) and light decrements (offsets = dark spots) on a uniform background were determined in each eye and the visual field scores were calculated for each of the subjects. Light offsets detected the presence of glaucomatous visual loss and also revealed significant early visual deficits which were missed by the conventional light onset stimuli. This study indicates that 'off-pathway' evaluation with light offsets can be used for the assessment of the functional integrity of the visual system and may reveal sub-clinical early glaucomatous optic neuropathy.

引用

页码：1159 / 1162

页数：4

共 25 条

[1]

ASAI T, 1987, Folia Ophthalmologica Japonica, V38, P701

[2] EVIDENCE FOR 2 SYSTEMS MEDIATING PERCEIVED CONTRAST [J].

BRANNAN, JR ;

BODISWOLLNER, I .

VISUAL NEUROSCIENCE, 1991, 6 (06) :587-592

[3]

CHATURVEDI N, 1983, INVEST OPHTH VIS SCI, V34, P1504

[4]

DAMATO BE, 1993, PERIMETRY UDATE 92 9, pCH7

[5] STRUCTURAL BASIS FOR ON-CENTER AND OFF-CENTER RESPONSES IN RETINAL GANGLION-CELLS [J].

FAMIGLIETTI, EV ;

KOLB, H .

SCIENCE, 1976, 194 (4261) :193-195

[6]

FLAMMER J, 1985, INVEST OPHTH VIS SCI, V26, P176

[7]

HART WM, 1979, ARCH OPHTHALMOL-CHIC, V97, P1455

[8] PLATELET-AGGREGATION, DISK HEMORRHAGE AND PROGRESSIVE LOSS OF VISUAL-FIELDS IN GLAUCOMA - A 7-YEAR FOLLOW-UP-STUDY ON GLAUCOMA [J].

HOYNG, PFJ ;

DEJONG, N ;

OOSTING, H ;

STILMA, J .

INTERNATIONAL OPHTHALMOLOGY, 1992, 16 (02) :65-73

[9] RETINAL AFFERENT ARBORIZATION PATTERNS, DENDRITIC FIELD ORIENTATIONS, AND THE SEGREGATION OF FUNCTION IN THE LATERAL GENICULATE-NUCLEUS OF THE MONKEY [J].

MICHAEL, CR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (13) :4914-4918

[10]

MORRISON JC, 1990, ARCH OPHTHALMOL-CHIC, V108, P1010

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