EFFECT OF EPIDIDYMAL ADMINISTRATION OF FREUNDS COMPLETE ADJUVANT ON AUTOIMMUNE-RESPONSE TO SPERMATOZOA IN VASECTOMIZED RATS

被引:0
|
作者
ALLAG, IS [1 ]
WARIKOO, PK [1 ]
DAS, RP [1 ]
ROY, S [1 ]
机构
[1] NATL INST HLTH & FAMILY WELF, DEPT REPROD BIOMED, NEW DELHI 110016, INDIA
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中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Intra-epididymal administration of Freund''s complete adjuvant causes an inflammatory reaction in the epididymis, which enhances the vasectomy related immuno-pathological changes in rats. The immuno-reactants are transferred from the epididymis to the seminiferous tubules through rete-testis in a retro-grade manner. This might explain the hypospermatogenesis after vasectomy. The androgen level may also be affected in case of severe auto-immune orchitis.
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页码:363 / 366
页数:4
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