CHEMICAL SYNTHESIS OF ALLYSINE ETHYLENE ACETAL AND CONVERSION IN-SITU INTO 1-PIPERIDEINE-6-CARBOXYLIC ACID - KEY INTERMEDIATE OF THE ALPHA-AMINOADIPIC ACID FOR BETA-LACTAM ANTIBIOTICS BIOSYNTHESIS

被引：24

作者：

RUMBERO, A

MARTIN, JF

LUMBRERAS, MA

LIRAS, P

ESMAHAN, C

机构：

[1] UNIV AUTONOMA MADRID,DEPT QUIM ORGAN,E-28049 MADRID,SPAIN

[2] UNIV LEON,FAC BIOL,DEPT ECOL GENET & MICROBIOL,E-24071 LEON,SPAIN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 1995年 / 3卷 / 09期

关键词：

D O I：

10.1016/0968-0896(95)00110-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Synthesis of alpha-amino acid allysine ethylene acetal from 3,4-dihydro-2H-pyran and its conversion in situ into 1-piperideine-6-carboxylic acid with an exceedingly simple work-up are described.

引用

页码：1237 / 1240

页数：4

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