EFFECT OF DISSOLVED-OXYGEN CONCENTRATION AND IMPELLER TIP SPEED ON ITACONIC ACID PRODUCTION BY ASPERGILLUS-TERREUS

被引:37
作者
PARK, YS [1 ]
OHTA, N [1 ]
OKABE, M [1 ]
机构
[1] SHIZUOKA UNIV,FAC AGR,DEPT APPL BIOL CHEM,BIOCHEM ENGN LAB,836 OHYA,OYA,SHIZUOKA 422,JAPAN
关键词
D O I
10.1007/BF00138544
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Effect of aeration rate and impeller tip speed on mucelium growth and itaconic acid production was investigated in a batch culture of Aspergillus terreus IFO-6365. When impeller tip speed was 94.2 cm/sec at a fixed aeration rate of 0.5 vvm, itaconic acid concentration was 3.6 and 1.6 times higher than those in the impeller tip speed of 62.8 and 125.7 cm/sec, respectively. When an oxygen-enriched air was supplied at a fixed impeller tip speed of 94.2 cm/sec and dissolved oxygen concentration was maintained in the 20-60% range, both itaconic acid concentration and mycelium growth were not affected by the dissolved oxygen concentration.
引用
收藏
页码:583 / 586
页数:4
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