IDENTIFICATION OF NOVEL MEMBERS OF G-PROTEIN COUPLED RECEPTOR SUPERFAMILY EXPRESSED IN BOVINE TASTE TISSUE

被引：42

作者：

MATSUOKA, I

MORI, T

AOKI, J

SATO, T

KURIHARA, K

机构：

[1] Faculty of Pharmaceutical Sciences, Hokkaido University

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 194卷 / 01期

关键词：

D O I：

10.1006/bbrc.1993.1848

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Using reverse transcription-polymerase chain reaction (RT-PCR) and degenerate oligonucleotide primers, we amplified novel members of two different subfamily of G-protein coupled receptor (GCR) superfamily from bovine taste tissue. Type A receptor clones composed of multiple cDNA clones had significant similarity with putative olfactory receptor subfamily, while a single type B clone had significant similarity with peptide receptor subfamily. Physiological functions of these receptors in taste cells are discussed. © 1993 Academic Press, Inc.

引用

收藏

页码：504 / 511

页数：8

相关论文

共 16 条

[1] MULTIPLE GENES FOR G-PROTEIN-COUPLED RECEPTORS AND THEIR EXPRESSION IN LINGUAL EPITHELIA [J].

ABE, K ;

KUSAKABE, Y ;

TANEMURA, K ;

EMORI, Y ;

ARAI, S .

FEBS LETTERS, 1993, 316 (03) :253-256

[2]

BEIDLER LM, 1985, TASTE OLFACTION CENT, P47

[3] A NOVEL MULTIGENE FAMILY MAY ENCODE ODORANT RECEPTORS - A MOLECULAR-BASIS FOR ODOR RECOGNITION [J].

BUCK, L ;

AXEL, R .

CELL, 1991, 65 (01) :175-187

[4] SINGLE-STEP METHOD OF RNA ISOLATION BY ACID GUANIDINIUM THIOCYANATE PHENOL CHLOROFORM EXTRACTION [J].

CHOMCZYNSKI, P ;

SACCHI, N .

ANALYTICAL BIOCHEMISTRY, 1987, 162 (01) :156-159

[5] MODEL SYSTEMS FOR THE STUDY OF 7-TRANSMEMBRANE-SEGMENT RECEPTORS [J].

DOHLMAN, HG ;

THORNER, J ;

CARON, MG ;

LEFKOWITZ, RJ .

ANNUAL REVIEW OF BIOCHEMISTRY, 1991, 60 :653-688

[6] LOCALIZATION OF PHOSPHATIDYLINOSITOL SIGNALING COMPONENTS IN RAT TASTE CELLS - ROLE IN BITTER TASTE TRANSDUCTION [J].

HWANG, PM ;

VERMA, A ;

BREDT, DS ;

SNYDER, SH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (19) :7395-7399

[7] RESPONSES OF FROG GUSTATORY RECEPTORS TO VARIOUS ODORANTS [J].

KASHIWAGURA, T ;

KAMO, N ;

KURIHARA, K ;

KOBATAKE, Y .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 1977, 56 (02) :105-108

[8] THE SCANNING MODEL FOR TRANSLATION - AN UPDATE [J].

KOZAK, M .

JOURNAL OF CELL BIOLOGY, 1989, 108 (02) :229-241

[9] SELECTIVE AMPLIFICATION AND CLONING OF 4 NEW MEMBERS OF THE G-PROTEIN COUPLED RECEPTOR FAMILY [J].

LIBERT, F ;

PARMENTIER, M ;

LEFORT, A ;

DINSART, C ;

VANSANDE, J ;

MAENHAUT, C ;

SIMONS, MJ ;

DUMONT, JE ;

VASSART, G .

SCIENCE, 1989, 244 (4904) :569-572

[10] SPATIAL PATTERN OF RECEPTOR EXPRESSION IN THE OLFACTORY EPITHELIUM [J].

NEF, P ;

HERMANSBORGMEYER, I ;

ARTIERESPIN, H ;

BEASLEY, L ;

DIONNE, VE ;

HEINEMANN, SF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (19) :8948-8952