Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation

被引：13
作者：
Kiggundu, Reuben [1 ]
Rhein, Joshua [1 ,2 ,3 ]
Meya, David B. [1 ,2 ,3 ]
Boulware, David R. [2 ,3 ]
Bahr, Nathan C. [1 ,2 ,3 ]
机构：
[1] Makerere Univ, Infect Dis Inst, Kampala, Uganda
[2] Univ Minnesota, Dept Med, Div Infect Dis & Int Med, Minneapolis, MN 55417 USA
[3] Univ Minnesota, Ctr Infect Dis & Microbiol Translat Res, Minneapolis, MN 55417 USA
来源：
MEDICAL MYCOLOGY CASE REPORTS | 2014年 / 5卷
关键词：
Cryptococcus meningitis; Immune reconstitution inflammatory syndrome; Postpartum; HIV; AIDS; Pregnancy;
D O I：
10.1016/j.mmcr.2014.05.001
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Cryptococcosis is the most common cause of meningitis in Africa due to the high burden of HIV. Immune reconstitution inflammatory syndrome (IRIS) is a frequent and deadly complication of cryptococcal meningitis. We report a fatal case of cryptococcal-IRIS in a pregnant woman that began after starting antiretroviral therapy (unmasking IRIS) and markedly worsened postpartum after delivery (paradoxical IRIS). (C) 2014 The Authors. International Society for Human and Animal Mycology. Published by Elsevier B.V.
引用
收藏
页码：16 / 19
页数：4
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