ALTERATION BY ILOPROST OF THE VASOSPASTIC EFFECTS OF ENDOTHELIN-1 IN RABBIT CEREBRAL VESSELS

被引：12
作者：
KESKIL, IS
BAYKANER, MK
SENCER, H
ATAOGLU, O
ILGIT, E
ERDOGAN, B
CEVIKER, N
ERCAN, ZS
机构：
[1] GAZI UNIV,FAC MED,DEPT NEUROSURG,ANKARA,TURKEY
[2] GAZI UNIV,FAC MED,DEPT PATHOL,ANKARA,TURKEY
[3] GAZI UNIV,FAC MED,DEPT RADIOL,ANKARA,TURKEY
[4] GAZI UNIV,FAC MED,DEPT PHARMACOL,ANKARA,TURKEY
[5] ANKARA UNIV,FAC MED,ELECTRON MICROSCOPY UNIT,ANKARA,TURKEY
来源：
NEUROREPORT | 1994年 / 5卷 / 09期
关键词：
CEREBRAL VASOSPASM; BASILAR ARTERY; ULTRASTRUCTURE; RABBIT; ENDOTHELIN-1; ILOPROST; ENDOTHELIAL CELL;
D O I：
10.1097/00001756-199405000-00017
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
THE reversal of endothelin-1 induced cerebral vasospasm with Iloprost was studied in the rabbit. Vasospasm in the basilar artery was evaluated by angiography; cerebral ischaemia by 'red-neurone-count' on light microscopy and morphological changes by electron microscopy. A potent antagonistic effect of Iloprost against ET-1 was observed in each of the parameters measured.
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收藏
页码：1089 / 1092
页数：4
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