CARBONYLATIVE COUPLING OF AN AMINO ACID-DERIVED ORGANOZINC REAGENT WITH FUNCTIONALIZED ARYL IODIDES - SYNTHESIS OF KYNURENINE

被引：13

作者：

JACKSON, RFW ^{[1
]}

TURNER, D ^{[1
]}

BLOCK, MH ^{[1
]}

机构：

[1] ZENECA PHARMACEUT,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 21期

关键词：

D O I：

10.1039/c39950002207

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The utility of the palladium(0) catalysed reaction of the serine-derived organozinc reagent 6 with functionalized aryl iodides, under a carbon monoxide atmosphere, to give protected 4-aryl-4-oxo alpha-amino acids 8 is illustrated by a short synthesis of L-kynurenine.

引用

页码：2207 / 2208

页数：2

共 8 条

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