FURAN FATTY-ACIDS DETERMINED AS OXIDATION-PRODUCTS OF CONJUGATED OCTADECADIENOIC ACID

被引：103
作者：
YURAWECZ, MP
HOOD, JK
MOSSOBA, MM
ROACH, JAG
KU, Y
机构：
[1] Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, Washington, 20204, DC
来源：
LIPIDS | 1995年 / 30卷 / 07期
关键词：
D O I：
10.1007/BF02536995
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The objective of this study was to identify oxidation products of conjugated linoleic acid (CLA), a series of octadecadienoic acids with conjugated double bonds, which have been reported to have antioxidant and anticarcinogenic properties. Reference materials of CLA were oxidized in different concentrations of water/methanol; for example, 0.5 g octadecadienoic acid was dissolved in 50 mL methanol, and 100 mL water was added; this suspension was heated at 50 degrees C and continuously aerated. Aliquots of 5 mL were taken over time, extracted with ether, treated with diazomethane and examined by gas chromatography/mass spectrometry and/or gas chromatography with flame-ionization detection. Products identified included the following furan fatty acids (FFAs): 8,11-epoxy-8,10-octadecadienoic; 9,12-epoxy-9,11-octadecadienoic; 10,13-epoxy-10,12-octadecadienoic; and 11,14-epoxy-11,13-octadecadienoic. Conjugated dienes should be considered as a possible source of FFAs, and CLA may have products common to furans in their overall oxidative scheme.
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页码：595 / 598
页数：4
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