NEPHROTIC SYNDROME WITH MASSIVE ACCUMULATION OF TYPE-I AND TYPE-III COLLAGEN IN THE GLOMERULI

被引：22
作者：
YOSHIDA, F
YUZAWA, Y
SHIGEMATSU, H
ITO, A
YAMAZAKI, C
YOSHIOKA, K
OOSHIMA, A
MATSUO, S
机构：
[1] Third Department of Internal Medicine, Nagoya University School of Medicine, Nagoya
[2] First Department of Pathology, Shinshu University School of Medicine, Matsumoto
[3] Masuko Memorial Hospital, Nagoya
[4] Department of Pediatrics, Kinki University School of Medicine, Osaka
[5] First Department of Pathology, Wakayama Prefectural University School of Medicine, Wakayama
来源：
INTERNAL MEDICINE | 1993年 / 32卷 / 02期
关键词：
HUMAN; GLOMERULUS; COLLAGENOUS FIBERS; SUBENDOTHELIAL EXPANSION;
D O I：
10.2169/internalmedicine.32.171
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 54-year-old woman with nephrotic syndrome underwent renal biopsy. By light microscopy, the glomerular capillary lumen was remarkably narrowed because of diffuse accumulation of Periodic acid Shiff (PAS) positive material along the glomerular capillary wall. By electron microscopy, collagenous fibers were observed in the mesangium and subendothelial area. The fibrous material reacted with antibodies against type I and III collagen but not with those against laminin or type IV collagen by an indirect immunofluorescence technique. This case seemed to be a case of collagenofibrotic glomerulonephropathy.
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页码：171 / 176
页数：6
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